- ￥880
- Bioss
- bs-15408P
- 2025年10月16日
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500ug
| 产品编号 | bs-15408P |
| 英文名称 | H-2Dd Antibody Blocking Peptide |
| 中文名称 | I类组织相容性H-2抗原D-Dalpha链封闭多肽 |
| 英文别名 | H-2 class I histocompatibility antigen, D-D alpha chain; H-2D(D); HA12_MOUSE. |
| 纯化方法 | HPLC |
| 研究领域 | Immunology > Adaptive Immunity > MHC > Class I |
| 亚基 | Heterodimer of an alpha chain and a beta chain (beta-2-microglobulin). |
| 亚细胞定位 | Membrane; Single-pass type I membrane protein. |
| 相似性 | Belongs to the MHC class I family. Contains 1 Ig-like C1-type (immunoglobulin-like) domain. |
| 功能 | Involved in the presentation of foreign antigens to the immune system. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Predicted to enable several functions, including 14-3-3 protein binding activity; TAP binding activity; and signaling receptor binding activity. Acts upstream of or within antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent; negative regulation of neuron projection development; and positive regulation of T cell mediated cytotoxicity. Located in external side of plasma membrane. Colocalizes with membrane raft. Is expressed in several structures, including alimentary system; brain; early conceptus; genitourinary system; and hemolymphoid system gland. Human ortholog(s) of this gene implicated in several diseases, including asthma (multiple); autoimmune disease (multiple); eye disease (multiple); Human immunodeficiency virus infectious disease (multiple); and inner ear disease (multiple). Orthologous to several human genes including HLA-A (major histocompatibility complex, class I, A); HLA-B (major histocompatibility complex, class I, B); and HLA-C (major histocompatibility complex, class I, C). [provided by Alliance of Genome Resources, Apr 2022] |
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H-2Dd Antibody Blocking Peptide(bs-15408P)-500ug
￥880
