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- Bioss
- bs-15401P
- 2025年10月16日
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500ug
| 产品编号 | bs-15401P |
| 英文名称 | H2BFWT Antibody Blocking Peptide |
| 中文名称 | H2B组蛋白家族成员W蛋白(睾丸特异性)封闭多肽 |
| 英文别名 | H2B histone family member W testis-specific; H2BFWT; H2BWT_HUMAN; Histone H2B type W-T. |
| 纯化方法 | HPLC |
| 研究领域 | Epigenetics and Nuclear Signaling > Chromosome Structure > Telomeres Epigenetics and Nuclear Signaling > Histones > H2B > Unmodified |
| 亚基 | The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. |
| 亚细胞定位 | Nucleus membrane. Chromosome. |
| 组织特异性 | Testis-specific. Present in sperm cells (at protein level). |
| 相似性 | Belongs to the histone H2B family. |
| 功能 | Atypical histone H2B. Nucleosomes containing it are structurally and dynamically indistinguishable from those containing conventional H2B. However, unlike conventional H2B, does not recruit chromosome condensation factors and does not participate in the assembly of mitotic chromosomes. May be important for telomere function. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the H2B histone family that is specifically expressed in sperm nuclei. A polymorphism in the 5' UTR of this gene is associated with male infertility.[provided by RefSeq, Oct 2015] |
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H2BFWT Antibody Blocking Peptide(bs-15401P)-500ug
￥880
