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- bs-16885P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-16885P |
| 英文名称 | KCNH4 Antibody Blocking Peptide |
| 中文名称 | KCNH4蛋白封闭多肽 |
| 英文别名 | BEC2; Brain-specific eag-like channel 2; ELK channel 1; ELK channel 1; brain-specific eag-like channel 2; ELK1; Ether-a-go-go K(+) channel family member; Ether-a-go-go-like potassium channel 1; Kv12.3; OTTMUSP00000002054; OTTMUSP00000002055; Potassium voltage gated channel, subfamily H (eag-related), member 4; RP23-390D17.9; Voltage-gated potassium channel subunit Kv12.3. |
| 纯化方法 | HPLC |
| 亚基 | he potassium channel is probably composed of a homo- or heterotetrameric complex of pore-forming alpha subunits that can associate with modulating beta subunits. |
| 亚细胞定位 | Membrane; Multi-pass membrane protein. |
| 组织特异性 | Detected only in brain, in particular in the telencephalon. Detected in putamen and caudate nucleus, and at lower levels in cerebral cortex, occipital and hippocampus. |
| 相似性 | Belongs to the potassium channel family. H (Eag) (TC 1.A.1.20) subfamily. Kv12.3/KCNH4 sub-subfamily. Contains 1 cyclic nucleotide-binding domain. Contains 1 PAC (PAS-associated C-terminal) domain. Contains 1 PAS (PER-ARNT-SIM) domain. |
| 功能 | Pore-forming (alpha) subunit of voltage-gated potassium channel. Elicits an outward current, but shows no inactivation. Channel properties may be modulated by cAMP and subunit assembly. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit. The gene is brain-specific, and located in the neocortex and the striatum. It may be involved in cellular excitability of restricted neurons in the central nervous system. [provided by RefSeq, Jul 2008] |
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KCNH4 Antibody Blocking Peptide(bs-16885P)-500ug
￥880
