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500ug
| 产品编号 | bs-16880P |
| 英文名称 | L3MBTL2 Antibody Blocking Peptide |
| 中文名称 | 致死因子恶性脑瘤样蛋白2封闭多肽 |
| 英文别名 | 3bt like 2 protein; 3bt like protein; DKFZP761I141; H-l(3)mbt-like protein 2; H-l(3)mbt-like protein; Hl; Hl(3)mbt like protein; Hl(3)mbtl; L; l(3)mbt like 2 (Drosophila); l(3)mbt like 2; L(3)mbt-like 2 protein; L(3)mbt-like protein 2; L3MBTL2; Lethal; Lethal(3)malignant brain tumor-like 2 protein; Lethal(3)malignant brain tumor-like protein 2; LMBL2_HUMAN. |
| 纯化方法 | HPLC |
| 研究领域 | Cell Biology > Cell Cycle > Cell Cycle Inhibitors Epigenetics and Nuclear Signaling > Chromatin Remodeling > Polycomb Silencing |
| 亚基 | Part of the E2F6.com-1 complex in G0 phase composed of E2F6, MGA, MAX, TFDP1, CBX3, BAT8, EUHMTASE1, RING1, RNF2, MBLR,BAT8 and YAF2. |
| 亚细胞定位 | Nucleus. |
| 相似性 | Contains 1 FCS-type zinc finger. Contains 4 MBT repeats. |
| 功能 | Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Its association with a chromatin-remodeling complex suggests that it may contribute to prevent expression of genes that trigger the cell into mitosis. Binds to monomethylated and dimethylated 'Lys-20' on histone H4. Binds histone H3 peptides that are monomethylated or dimethylated on 'Lys-4', 'Lys-9' or'Lys-27'. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Its association with a chromatin-remodeling complex suggests that it may contribute to prevent expression of genes that trigger the cell into mitosis. Binds to monomethylated and dimethylated 'Lys-20' on histone H4. Binds histone H3 peptides that are monomethylated or dimethylated on 'Lys-4', 'Lys-9' or 'Lys-27'. |
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文献和实验or from the literature are missing. In this article, processing parameters for DNA, peptide, antibody, and carbohydrate microarrays are outlined. The applicability of the model experiments is demonstrated and described in detail on the example of short oligonucleotides.
Synthesis and Probing of Membrane-bound Peptide Arrays
the stringency of the blocking conditions and make sure that the primary binding partner and detection reagent (e.g., antibody) are of high purity and are used in the highest possible dilution. Stage
Mapping Protein‐Protein Interactions with Phage‐Displayed Combinatorial Peptide Libraries
. Fack, F., Deroo, S., Kreis, S., and Muller, C.P. 2000. Heteroduplex mobility assay (HMA) pre‐screening: An improved strategy for the rapid identification of inserts selected from phage‐displayed peptide
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