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- bs-16872P
- 2025年10月16日
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- 规格：
500ug
| 产品编号 | bs-16872P |
| 英文名称 | ODCp Antibody Blocking Peptide |
| 中文名称 | 精氨酸脱羧酶封闭多肽 |
| 英文别名 | L-Arginine decarboxylase; ADC; ADC_HUMAN; Antizyme inhibitor 2; ArgDC; Arginine decarboxylase; AZI2; KIAA1945; L-Arginine carboxy lyase; ODC antizyme inhibitor 2; ODC paralog; ODC-p; ODC-paralogue; ODC1L; ODCp; Ornithine decarboxylase like; Ornithine decarboxylase paralog; Ornithine decarboxylase-like protein. |
| 纯化方法 | HPLC |
| 研究领域 | Metabolism > Pathways and Processes > Metabolic signaling pathways > Amino acid metabolism Signal Transduction > Metabolism > Amino Acids |
| 亚基 | Interacts with OAZ1, OAZ2 and OAZ3; the interactions stabilize the complex by inhibiting AZIN2 ubiquitination and degradation. Does not form an heterodimer with ODC1 (By similarity). Monomer. Interaction with OAZ1, OAZ2 and OAZ3; the interactions lead to increased ornithine decarboxylase (ODC)activity and decreased rate of ODC1 degradation. |
| 亚细胞定位 | Nucleus. |
| 组织特异性 | Highly expressed in brain. Also expressed in testis. |
| 相似性 | Belongs to the Orn/Lys/Arg decarboxylase class-II family. |
| 功能 | Decarboxylates L-arginine to agmatine. Truncated splice isoforms probably lack activity. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | ODCp is a 460 amino acid protein that is expressed in brain and testis. ODCp is a member of the Orn/Lys/Arg decarboxylase class-II family that catalyzes the creation of CO2 and agmatine from L-arginine. Mammalian ODCp differs from the forms expressed in bacteria and plants and shares less than 50% homology with Ornithine decarboxylase (ODC). ODCp is associated with the mitochondrial membrane where excess agmatine can be degraded by the enzyme Agmatinase or bound by the imidazoline recepto. In the brain, the highest levels of ODCp are found in the hypothalamus. Mammalian ODCp is thermally unstable and can be inhibited by Ca2+, Co2+ and polyamines. |
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ODCp Antibody Blocking Peptide(bs-16872P)-500ug
￥880
