GALR3 Antibody Blocking Peptide(bs-11528P)-500ug

GALR3 Antibody Blocking Peptid

e(bs-11528P)-500ug
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  • ¥880
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  • bs-11528P
  • 2025年10月16日
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    • 规格

      500ug

    产品编号bs-11528P
    英文名称GALR3 Antibody Blocking Peptide
    中文名称甘丙肽受体3封闭多肽
    英文别名GAL 3R; GAL R3; GAL3 R; GAL3-R; GAL3R; Galanin receptor 3; Galanin receptor-3; Galanin receptor family member 3; Galanin receptor type 3; GALN R3; GALNR 3; GALNR3; GALR 3; GALR-3; Galr3; GALR3_HUMAN.
    纯化方法HPLC
    研究领域

    Neuroscience > Neurotransmission > Receptors / Channels > GPCR > More GPCR

    亚细胞定位Cell membrane; Multi-pass membrane protein.
    相似性Belongs to the G-protein coupled receptor 1 family.
    功能Receptor for the hormone galanin.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料GALR3 a 368 and 370 amino acid protein in human and rat, respectively, belongs to a family of G protein-coupled receptors that bind the neuropeptide galanin, which is distributed throughout the central and peripheral nervous system, the pituitary gland, the gastrointestinal tract and in the endocrine and exocrine pancreas. GALR3 mRNA is widely distributed, but expressed at low abundance. In human, GALR3 mRNA is highly expressed in the hypothalamus, pituitary and testis, and is expressed to a lesser extent in adrenal gland and pancreas. Rat and human GALR3 co-express with potassium channel subunits GIRK1 and GIRK4. Like GALR1, GALR3 signaling pathways lead to the inhibition of adenylate cyclase and to the activation of potassium channels, which are linked to the regulation of neurotransmitter release. Binding of galanin to galanin receptors results in increased feeding, impaired learning, enhanced opiate analgesia and decreased opiate place preference.

     

     

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