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500ug
| 产品编号 | bs-14067P |
| 英文名称 | CROP Antibody Blocking Peptide |
| 中文名称 | 环磷酸腺苷调节元件相关蛋白1封闭多肽 |
| 英文别名 | cAMP regulatory element-associated protein 1; Cisplatin resistance-associated overexpressed protein; Cisplatin resistance-associated-overexpressed protein; CRE-associated protein 1; CREAP-1; CREAP1; CROP; LC7L3_HUMAN; Luc7-like protein 3; Luc7A; LUC7L3; O48; Okadaic acid-inducible phosphoprotein OA48-18. |
| 纯化方法 | HPLC |
| 研究领域 | Epigenetics and Nuclear Signaling > DNA / RNA > DNA Damage & Repair > DNA Damage Response > ATM / ATR Epigenetics and Nuclear Signaling > DNA / RNA > RNA Processing > Splicing |
| 亚细胞定位 | Nucleus speckle. The subnuclear localization is affected by cisplatin. |
| 组织特异性 | Widely expressed. Highest levels in heart, brain, pancreas, thymus, ovary, small intestine and peripheral blood leukocytes, as well as cerebellum, putamen and pituitary gland. Lowest levels in lung, liver and kidney. Also expressed in fetal tissues, including brain, heart, kidney, thymus and lung. |
| 翻译后修饰 | Phosphorylated in vitro by SRPK1, SRPK2 and CLK1. Phosphorylated upon DNA damage, probably by ATM or ATR. |
| 相似性 | Belongs to the Luc7 family. |
| 功能 | Binds cAMP regulatory element DNA sequence. May play a role in RNA splicing. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes a protein with an N-terminal half that contains cysteine/histidine motifs and leucine zipper-like repeats, and the C-terminal half is rich in arginine and glutamate residues (RE domain) and arginine and serine residues (RS domain). This protein localizes with a speckled pattern in the nucleus, and could be involved in the formation of splicesome via the RE and RS domains. Two alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Aug 2009] |
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CROP Antibody Blocking Peptide(bs-14067P)-500ug
¥880







