PPFIBP1 Antibody Blocking Peptide(bs-21057P)-500ug

PPFIBP1 Antibody Blocking Pept

ide(bs-21057P)-500ug
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  • bs-21057P
  • 2025年10月16日
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      500ug

    产品编号bs-21057P
    英文名称PPFIBP1 Antibody Blocking Peptide
    中文名称PTPRF相互作用蛋白结合蛋白1封闭多肽
    英文别名PPFIBP 1; hSGT2; hSgt2p; KIAA1230; KIAA1230; L2; LIPB1_HUMAN; Liprin beta 1; liprin related protein; Liprin-beta-1; PPFIBP 1; PPFIBP1; Protein tyrosine phosphatase receptor type f polypeptide interacting protein binding protein 1; Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1; PTPRF interacting protein binding protein 1; PTPRF interacting protein, binding protein 1 (liprin beta 1); PTPRF-interacting protein-binding protein 1; SGT2.
    纯化方法HPLC
    研究领域

    Signal Transduction > Protein Phosphorylation > Tyrosine Phosphatases

    组织特异性Widely expressed. Absent in liver.
    相似性Belongs to the liprin family. Liprin-beta subfamily.
    Contains 3 SAM (sterile alpha motif) domains.
    功能May regulate the disassembly of focal adhesions. Did not bind receptor-like tyrosine phosphatases type 2A.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. It has been proposed that liprins are multivalent proteins that form complex structures and act as scaffolds for the recruitment and anchoring of LAR family of tyrosine phosphatases. This protein was found to interact with S100A4, a calcium-binding protein related to tumor invasiveness and metastasis. In vitro experiment demonstrated that the interaction inhibited the phosphorylation of this protein by protein kinase C and protein kinase CK2. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

     

     

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