POMZP3 Antibody Blocking Peptide(bs-21041P)-500ug

POMZP3 Antibody Blocking Pepti

de(bs-21041P)-500ug
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  • bs-21041P
  • 2025年10月16日
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      500ug

    产品编号bs-21041P
    英文名称POMZP3 Antibody Blocking Peptide
    中文名称POMZP3蛋白封闭多肽
    英文别名MGC8359; OTTHUMP00000208707; OTTHUMP00000208708; POM (POM121 homolog rat) and ZP3 fusion; POM (POM121 rat homolog) and ZP3 fusion; POM 121; POM and ZP3 fusion; POM ZP3; POM ZP3 fusion protein; POM-ZP3; POM121 and ZP3 fusion protein; POM121; POM121/ZP3 fusion protein; POMZP 3; POMZP3; POMZP3 fusion protein; POZP3_HUMAN.
    纯化方法HPLC
    亚细胞定位Secreted > extracellular space > extracellular matrix and Cell membrane.
    组织特异性Expressed in spleen, thymus, pancreas, testis, ovary, small intestine, colon and lymphocytes.
    翻译后修饰Proteolytically cleaved before the transmembrane segment to yield the secreted ectodomain incorporated in the zona pellucida.
    N-glycosylated.
    O-glycosylated; removal of O-linked glycans may play an important role in the post-fertilization block to polyspermy.
    功能The mammalian zona pellucida, which mediates species-specific sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy, is composed of three to four glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP3 is essential for sperm binding and zona matrix formation.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料This gene appears to have resulted from a fusion of DNA sequences derived from 2 distinct loci, specifically through the duplication of two internal exons from the POM121 gene and four 3' exons from the ZP3 gene. The 5' end of this gene is similar to the 5` coding region of the POM121 gene which encodes an integral nuclear pore membrane protein. However, the protein encoded by this gene lacks the nuclear pore localization motif. The 3' end of this gene is similar to the last 4 exons of the zona pellucida glycoprotein 3 (ZP3) gene and the encoded protein retains one zona pellucida domain. Multiple protein isoforms are encoded by transcript variants of this gene. [provided by RefSeq, Jul 2008]

     

     

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