PAOX Antibody Blocking Peptide(bs-21016P)-500ug

PAOX Antibody Blocking Peptide

(bs-21016P)-500ug
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  • ¥880
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  • bs-21016P
  • 2025年10月16日
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      500ug

    产品编号bs-21016P
    英文名称PAOX Antibody Blocking Peptide
    中文名称多胺氧化酶PAOX封闭多肽
    英文别名DKFZp434J245; MGC45464; PAO; Peroxisomal N(1) acetyl spermine/spermidine oxidase; Peroxisomal N1 acetyl spermine/spermidine oxidase; Polyamine oxidase (exo N4 amino); Polyamine oxidase; RP11 122K13.11.
    纯化方法HPLC
    研究领域

    Metabolism > Pathways and Processes > Metabolic signaling pathways > Energy transfer pathways > Energy Metabolism

    Signal Transduction > Metabolism > Energy Metabolism

    亚细胞定位Peroxisome. Cytoplasm.
    组织特异性Widely expressed. Not detected in spleen. Expressed at lower level in neoplastic tissues.
    相似性Belongs to the flavin monoamine oxidase family.
    功能Flavoenzyme which catalyzes the oxidation of N(1)-acetylspermine to spermidine and is thus involved in the polyamine back-conversion. Can also oxidize N(1)-acetylspermidine to putrescine. Substrate specificity: N(1)-acetylspermine = N(1)-acetylspermidine > N1,N(12)-diacylspermine >> spermine. Does not oxidize spermidine. Plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料PAOX is a flavoenzyme which catalyzes the oxidation of N(1)-acetylspermine to spermidine and is thus involved in the polyamine back-conversion. It can also oxidize N(1)-acetylspermidine to putrescine. It does not oxidize spermidine. PAOX plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs. There are eleven named isoforms.

     

     

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