- ￥880 - 1380
- Bioss
- bs-4976P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug/1mg
| 规格： | 500ug | 产品价格： | ￥880.0 |
|---|---|---|---|
| 规格： | 1mg | 产品价格： | ￥1380.0 |
| 产品编号 | bs-4976P |
| 英文名称 | H5N1 Nucleoprotein Antibody Blocking Peptide |
| 中文名称 | A型流感病毒核蛋白封闭多肽 |
| 英文别名 | Nucleoprotein; NP; Nucleocapsid protein; Protein N; Influenza A virus H1N1; H3N2 Nucleoprotein; H9N2 Nucleoprotein; H2N2 Nucleoprotein; H3N8 Nucleoprotein; H7N7 Nucleoprotein; H5N1 Nucleoprotein. |
| 性状 | Lyophilized |
| 纯化方法 | HPLC |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | bs-4976P is one synthetic peptide derived from Influenza A virus H1N1 Nucleoprotein. Encapsidates the negative strand viral RNA, protecting it from nucleases. The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication. The RNP needs to be localized in the nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex. NP comprises at least 2 nuclear localization signals and is responsible of the active RNP import into the nucleus through the cellular importin alpha/beta pathway. Later in the infection, nucleus export of RNP are mediated through viral proteins NEP interacting with M1 which binds nucleoproteins. It is possible that the nucleoprotein binds directly exportin-1 (XPO1) and plays an active role in RNP nuclear export. M1 interaction with RNP seems to hide nucleoprotein's nuclear localization signals. Soon after a virion infects a new cell, M1 dissociates from the RNP under acidification of the virion driven by M2 protein. Dissociation of M1 from RNP unmask nucleoprotein's nuclear localization signals, targeting the RNP to the nucleus. |
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H5N1 Nucleoprotein Antibody Blocking Peptide(bs-4976P)-500ug/1mg
￥880 - 1380
