GPCR LGR7 Antibody Blocking Peptide(bs-15368P)-500ug

GPCR LGR7 Antibody Blocking Pe

ptide(bs-15368P)-500ug
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  • bs-15368P
  • 2025年10月16日
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      500ug

    产品编号bs-15368P
    英文名称GPCR LGR7 Antibody Blocking Peptide
    中文名称G蛋白偶联受体LGR7蛋白封闭多肽
    英文别名Gm1018; Leucine rich repeat containing G protein coupled receptor 7;LGR7; LGR7.1; LGR7.10; LGR7.2; MGC138347; MGC142177; Relaxin family peptide receptor 1; Relaxin receptor 1; Relaxin/insulin like family peptide receptor 1; RXFP 1; RXFP1; RXFP1; RXFP1_HUMAN; RXFPR1.
    纯化方法HPLC
    研究领域

    Signal Transduction > Signaling Pathway > G Protein Signaling > GPCR

    亚细胞定位Cell membrane; Multi-pass membrane protein.
    组织特异性Expressed in the brain, kidney, testis, placenta, uterus, ovary, adrenal, prostate, skin and heart. Not detected in spleen.
    相似性Belongs to the G-protein coupled receptor 1 family.
    Contains 1 LDL-receptor class A domain.
    Contains 9 LRR (leucine-rich) repeats.
    Contains 1 LRRNT domain.
    功能Receptor for relaxins. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. Binding of the ligand may also activate a tyrosine kinase pathway that inhibits the activity of a phosphodiesterase that degrades cAMP.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料This gene encodes a member of the leucine-rich repeat-containing subgroup of the G protein-coupled 7-transmembrane receptor superfamily. The encoded protein plays a critical role in sperm motility, pregnancy and parturition as a receptor for the protein hormone relaxin. Decreased expression of this gene may play a role in endometriosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]

     

     

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