- ￥880
- Bioss
- bs-21036P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-21036P |
| 英文名称 | RNPEP Antibody Blocking Peptide |
| 中文名称 | 精氨酸氨基肽酶B封闭多肽 |
| 英文别名 | Aminopeptidase B; AMPB_HUMAN; Ap B; AP-B; APB; Arginine aminopeptidase; Arginyl aminopeptidase (aminopeptidase B); Arginyl aminopeptidase; DKFZp547H084; RNPEP. |
| 纯化方法 | HPLC |
| 研究领域 | Cell Biology > Proteolysis / Ubiquitin > Proteolytic enzymes > Other proteases |
| 亚细胞定位 | Peroxisome. |
| 组织特异性 | Widely expressed with highest levels of isoform 1 and isoform 2 detected in testis. Isoform 1 is expressed at higher levels than isoform 2 in liver and kidney while isoform 2 levels are higher in brain, lung, muscle, white adipose tissue and testis. Levels are almost equal in heart. |
| 相似性 | Belongs to the acyl-CoA oxidase family. |
| 功能 | Catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. Isoform 1 shows highest activity against medium-chain fatty acyl-CoAs and activity decreases with increasing chain length. Isoform 2 is active against a much broader range of substrates and shows activity towards very long-chain acyl-CoAs. Isoform 2 is twice as active as isoform 1 against 16-hydroxy-palmitoyl-CoA and is 25% more active against 1,16-hexadecanodioyl-CoA. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Defects in ACOX1 are the cause of adrenoleukodystrophy pseudoneonatal (Pseudo-NALD); also known as peroxisomal acyl-CoA oxidase deficiency. Pseudo-NALD is a peroxisomal single-enzyme disorder. Clinical features include mental retardation, leukodystrophy, seizures, mild hepatomegaly, hearing deficit. Pseudo-NALD is characterized by increased plasma levels of very-long chain fatty cids, due to decreased or absent peroxisome acyl-CoA oxidase activity. Peroxisomes are intact and functioning. |
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RNPEP Antibody Blocking Peptide(bs-21036P)-500ug
￥880
