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500ug
| 产品编号 | bs-14048P |
| 英文名称 | CRCP Antibody Blocking Peptide |
| 中文名称 | 降钙素基因相关肽受体CRCP封闭多肽 |
| 英文别名 | Calcitonin gene related peptide receptor component; Calcitonin gene related peptide receptor component protein; Calcitonin gene-related peptide-receptor component protein; CGRP receptor component protein; CGRP-RCP; CGRP-receptor component protein; CGRPRCP; CRCP; DNA-directed RNA polymerase III subunit RPC9; HsC17; RCP; RCP9; RNA polymerase III subunit C9; RPC9_HUMAN. |
| 纯化方法 | HPLC |
| 研究领域 | Cardiovascular > Heart > Contractility > Inotropics Cardiovascular > Vasculature > Vasodilation Neuroscience > Neurotransmission > Receptors / Channels > GPCR > More GPCR Neuroscience > Neurotransmitter > Neuropeptides > Hormones Neuroscience > Neurotransmitter > Neuropeptides > More Neuropeptides Signal Transduction > Signaling Pathway > G Protein Signaling > GPCR |
| 亚细胞定位 | Nucleus. Cell membrane. |
| 组织特异性 | Ubiquitous. Most prevalent in testis. |
| 相似性 | Belongs to the eukaryotic RPC9 RNA polymerase subunit family. |
| 功能 | DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts induce type I interferon and NF- Kappa-B through the RIG-I pathway. Accessory protein for the calcitonin gene-related peptide (CGRP) receptor. It modulates CGRP responsiveness in a variety of tissues. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes a membrane protein that functions as part of a receptor complex for a small neuropeptide that increases intracellular cAMP levels. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008] |
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CRCP Antibody Blocking Peptide(bs-14048P)-500ug
¥880







