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500ug
| 产品编号 | bs-14038P |
| 英文名称 | CPSF6 Antibody Blocking Peptide |
| 中文名称 | 剪切及多聚腺苷酸化特异性因子6蛋白封闭多肽 |
| 英文别名 | CFIm68; Cleavage and polyadenylation specificity factor 68 kDa subunit; Cleavage and polyadenylation specificity factor subunit 6; CPSF 68 kDa subunit; Cpsf6; CPSF6_HUMAN; HPBRII 4; HPBRII 7; Pre mRNA cleavage factor Im 68 kDa subunit; Pre-mRNA cleavage factor Im 68 kDa subunit; Protein HPBRII 4/7; Protein HPBRII-4/7. |
| 纯化方法 | HPLC |
| 研究领域 | Epigenetics and Nuclear Signaling > DNA / RNA > RNA Processing |
| 亚细胞定位 | Nucleus. In punctate subnuclear structures localized adjacent to nuclear speckles, called paraspeckles. |
| 翻译后修饰 | Phosphorylated upon DNA damage, probably by ATM or ATR. |
| 相似性 | Belongs to the RRM CPSF6/7 family. Contains 1 RRM (RNA recognition motif) domain. |
| 功能 | Component of the cleavage factor Im complex (CFIm) that plays a key role in pre-mRNA 3'-processing. Involved in association with NUDT21/CPSF5 in pre-MRNA 3'-end poly(A) site cleavage and poly(A) addition. CPSF6 binds to cleavage and polyadenylation RNA substrates and promotes RNA looping. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The protein encoded by this gene is one subunit of a cleavage factor required for 3' RNA cleavage and polyadenylation processing. The interaction of the protein with the RNA is one of the earliest steps in the assembly of the 3' end processing complex and facilitates the recruitment of other processing factors. The cleavage factor complex is composed of four polypeptides. This gene encodes the 68kD subunit. It has a domain organization reminiscent of spliceosomal proteins. [provided by RefSeq, Jul 2008] |
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CPSF6 Antibody Blocking Peptide(bs-14038P)-500ug
¥880







