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- 规格:
500ug
| 产品编号 | bs-16853P |
| 英文名称 | KCP2 Antibody Blocking Peptide |
| 中文名称 | 角蛋白相关蛋白KCP2封闭多肽 |
| 英文别名 | KRTCAP2; KCP-2; KCP2; Keratinocyte-associated protein 2; KRTCAP2; KTAP2_HUMAN. |
| 纯化方法 | HPLC |
| 亚基 | Component of the oligosaccharyltransferase (OST) complex.OST seems to exist in different forms which contain at least RPN1,RPN2, OST48, DAD1, OSTC, KRTCAP2 and either STT3A or STT3B. OST can form stable complexes with the Sec61 complex or with both the Sec61 and TRAP complexes. Interacts with STT3A. |
| 亚细胞定位 | Endoplasmic reticulum membrane |
| 组织特异性 | Expressed in skin, heart, placental, liver, skeletal muscle, kidney, pancreas, keratinocytes and dermal fibroblasts. |
| 相似性 | Belongs to the KRTCAP2 family. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Acts as accessory component of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. Required for efficient substrate-specific N-glycosylation probably involving the STT3A-containing OST complex. May be involved in N-glycosylation of APP (amyloid-beta precursor protein). Can modulate gamma-secretase cleavage of APP by enhancing endoprotelysis of PSEN1. |
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KCP2 Antibody Blocking Peptide(bs-16853P)-500ug
¥880







