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- Bioss
- bs-12788P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-12788P |
| 英文名称 | ACP5 Antibody Blocking Peptide |
| 中文名称 | 酒石酸酸性磷酸酶5型封闭多肽 |
| 英文别名 | TRAP5; Acid phosphatase 5, tartrate resistant; ACP5; EC 3.1.3.2; phosphatase, acid, type 5, tartrate-resistant; PPA5_HUMAN; serum band 5 tartrate-resistant acid phosphatase; SPENCDI; Tartrate-resistant acid ATPase; Tartrate-resistant acid phosphatase type 5; TR-AP; TRACP 5; TRAcP; TRAP; TrATPase; Type 5 acid phosphatase. |
| 纯化方法 | HPLC |
| 研究领域 | Cancer > Tumor biomarkers > Enzymes > Phosphatases Cell Biology > Cell Cycle > Kinases/Phosphatases > Phosphatases Kits/ Lysates/ Other > Kits > Cell Metabolism Kits > Other Metabolism Assay |
| 亚基 | Exists either as monomer or, after proteolytic processing, as a dimer of two chains linked by disulfide bond(s). |
| 亚细胞定位 | Lysosome. |
| 相似性 | Belongs to the metallophosphoesterase superfamily. Purple acid phosphatase family. |
| 功能 | Defects in ACP5 are the cause of spondyloenchondrodysplasia with immune dysregulation (SPENCDI) [MIM:607944]. A disease characterized by vertebral and metaphyseal dysplasia, spasticity with cerebral calcifications, and strong predisposition to autoimmune diseases. The skeletal dysplasia is characterized by radiolucent and irregular spondylar and metaphyseal lesions that represent islands of chondroid tissue within bone. Note=ACP5 inactivating mutations result in a functional excess of phosphorylated osteopontin causing deregulation of osteopontin signaling and consequential autoimmune disease. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes an iron containing glycoprotein which catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is the most basic of the acid phosphatases and is the only form not inhibited by L(+)-tartrate. [provided by RefSeq, Aug 2008] |
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ACP5 Antibody Blocking Peptide(bs-12788P)-500ug
￥880
