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500ug
| 产品编号 | bs-11521P |
| 英文名称 | NPY5R Antibody Blocking Peptide |
| 中文名称 | 神经肽Y受体5封闭多肽 |
| 英文别名 | Neuropeptide Y receptor type 5; Neuropeptide Y receptor Y5; NPY 5R; NPY R5; NPY Y5; NPY Y5 receptor; NPY-Y5 receptor; NPY5 R; NPY5-R; NPY5R; NPY5R_HUMAN; NPYR 5; NPYR5; NPYY 5; NPYY5; NPYY5-R; Y5 receptor. |
| 纯化方法 | HPLC |
| 研究领域 | Neuroscience > Neurology process > Metabolism Neuroscience > Neurotransmission > Receptors / Channels > GPCR > More GPCR Neuroscience > Neurotransmitter > Neuropeptides > More Neuropeptides |
| 亚细胞定位 | Cell membrane; Multi-pass membrane protein. |
| 组织特异性 | Brain; hypothalamus. |
| 相似性 | Belongs to the G-protein coupled receptor 1 family. |
| 功能 | Receptor for neuropeptide Y and peptide YY. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. Seems to be associated with food intake. Could be involved in feeding disorders. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Pancreatic polypeptide (PP), neuropeptide Y (NPY), and peptide YY (PYY) are related 36-amino acid hormones. A number of structurally related receptors for these peptides have been isolated, NPY1-R, NPY2-R, NPY3-R, NPY4-R, NPY5-R, and NPY6-R. NPY4-R is expressed in several human tissues, including brain, coronary artery, and ileum. NPY4-R maps to human chromosome 10q11.2. NPY-5R, isolated from rat hypothalamus, encodes a 456-amino acid protein with less than 35% overall identity to known Y-type receptors. The human NPY5-R sequence is nearly identical to, but in the opposite orientation from, that of the human NPY1-R sequence. NPY5-R localizes to the paraventricular hypothalamic nucleus, the lateral hypothalamus, and other locations consistent with a role in the control of feeding behavior. The gene which encodes NPY5-R maps to human chromosome 4q32.2. NPY6-R is abundantly expressed in human heart and skeletal muscle and the gene which encodes NPY6-R maps to human chromosome 5q31. |
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NPY5R Antibody Blocking Peptide(bs-11521P)-500ug
¥880







