NPY5R Antibody Blocking Peptide(bs-11521P)-500ug

NPY5R Antibody Blocking Peptid

e(bs-11521P)-500ug
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  • ¥880
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  • bs-11521P
  • 2025年10月16日
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      500ug

    产品编号bs-11521P
    英文名称NPY5R Antibody Blocking Peptide
    中文名称神经肽Y受体5封闭多肽
    英文别名Neuropeptide Y receptor type 5; Neuropeptide Y receptor Y5; NPY 5R; NPY R5; NPY Y5; NPY Y5 receptor; NPY-Y5 receptor; NPY5 R; NPY5-R; NPY5R; NPY5R_HUMAN; NPYR 5; NPYR5; NPYY 5; NPYY5; NPYY5-R; Y5 receptor.
    纯化方法HPLC
    研究领域

    Neuroscience > Neurology process > Metabolism

    Neuroscience > Neurotransmission > Receptors / Channels > GPCR > More GPCR

    Neuroscience > Neurotransmitter > Neuropeptides > More Neuropeptides

    亚细胞定位Cell membrane; Multi-pass membrane protein.
    组织特异性Brain; hypothalamus.
    相似性Belongs to the G-protein coupled receptor 1 family.
    功能Receptor for neuropeptide Y and peptide YY. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. Seems to be associated with food intake. Could be involved in feeding disorders.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Pancreatic polypeptide (PP), neuropeptide Y (NPY), and peptide YY (PYY) are related 36-amino acid hormones. A number of structurally related receptors for these peptides have been isolated, NPY1-R, NPY2-R, NPY3-R, NPY4-R, NPY5-R, and NPY6-R. NPY4-R is expressed in several human tissues, including brain, coronary artery, and ileum. NPY4-R maps to human chromosome 10q11.2. NPY-5R, isolated from rat hypothalamus, encodes a 456-amino acid protein with less than 35% overall identity to known Y-type receptors. The human NPY5-R sequence is nearly identical to, but in the opposite orientation from, that of the human NPY1-R sequence. NPY5-R localizes to the paraventricular hypothalamic nucleus, the lateral hypothalamus, and other locations consistent with a role in the control of feeding behavior. The gene which encodes NPY5-R maps to human chromosome 4q32.2. NPY6-R is abundantly expressed in human heart and skeletal muscle and the gene which encodes NPY6-R maps to human chromosome 5q31.

     

     

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