- ￥880
- Bioss
- bs-11504P
- 2025年10月16日
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- 技术资料
- 规格：
500ug
| 产品编号 | bs-11504P |
| 英文名称 | ATRNL1 Antibody Blocking Peptide |
| 中文名称 | ATRNL1蛋白封闭多肽 |
| 英文别名 | ATRN1_HUMAN; ATRNL1; Attractin-like protein 1; KIAA0534. |
| 纯化方法 | HPLC |
| 研究领域 | Metabolism > Pathways and Processes > Metabolic signaling pathways > Energy transfer pathways > Energy Metabolism Neuroscience > Neurology process > Metabolism Neuroscience > Neurotransmission > Receptors / Channels > GPCR > More GPCR Signal Transduction > Metabolism > Energy Metabolism Signal Transduction > Signaling Pathway > G Protein Signaling > GPCR |
| 亚基 | Interacts with MC4R |
| 亚细胞定位 | Membrane; Single-pass type I membrane protein |
| 相似性 | Contains 1 C-type lectin domain. Contains 1 CUB domain. Contains 2 EGF-like domains. Contains 6 Kelch repeats. Contains 2 laminin EGF-like domains. Contains 5 PSI domains. |
| 功能 | May play a role in melanocortin signaling pathways that regulate energy homeostasis. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | ATRNL1 is a 1,379 amino acid single-pass type I membrane protein that may play a role in melanocortin signaling pathways that regulate energy homeostasis. The ATRNL1 protein contains a C-type lectin domain, a CUB domain, two EGF-like domains, six Kelch repeats, two laminin EGF-like domains and five PSI domains. ATRNL1 interacts with MC4-R in several regions known to be important in the regulation of energy homeostasis by melanocortins, such as the paraventricular nucleus of hypothalamus and the dorsal motor nucleus of the vagus. The ATRNL1 gene is conserved in dog, cow, mouse, rat, chicken, zebrafish and C. elegans, exists as two alternatively spliced isoforms and maps to human chromosome 10q25.3. Strong evidence of linkage to late-onset Alzheimer disease (LOAD) is linked to chromosome 10, which implicates a wide region and at least one disease-susceptibility locus. |
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ATRNL1 Antibody Blocking Peptide(bs-11504P)-500ug
￥880
