CRISP2 Antibody Blocking Peptide(bs-14059P)-500ug

CRISP2 Antibody Blocking Pepti

de(bs-14059P)-500ug
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  • ¥880
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  • bs-14059P
  • 2025年10月16日
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      500ug

    产品编号bs-14059P
    英文名称CRISP2 Antibody Blocking Peptide
    中文名称富含半胱氨酸分泌蛋白2封闭多肽
    英文别名Cancer/testis antigen 36; CRIS2_HUMAN; CRISP 2; CRISP-2; CRISP2; CT36; Cysteine rich secretory protein 2; Cysteine-rich secretory protein 2; GAPDL5; Glyceraldehyde 3 phosphate dehydrogenase like 5; Testis specific protein 1 (probe H4 1 p3 1); Testis specific protein TPX1; Testis-specific protein TPX-1; TPX1; TSP1.
    纯化方法HPLC
    研究领域

    Developmental Biology > Reproduction > Fertilisation

    Developmental Biology > Reproduction > Germ cell markers

    亚细胞定位Secreted.
    组织特异性Testis and epididymis.
    相似性Belongs to the CRISP family.
    功能May regulate some ion channels' activity and therebye regulate calcium fluxes during sperm capacitation.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Cysteine-rich secretory proteins (CRISPs) represent a family of evolutionarily conserved proteins which may play a role in the innate immune system and are transcriptionally regulated by androgens in several tissues. CRISP-1 coats the postacrosomal region of sperm heads as they pass through the epididymis. CRISP-1 is found in all regions of the epididymis, ductus deferens, seminal plasma and sperm. CRISP-2, also known as testis-specific protein TPX1 or cancer/testis antigen 36 (CT36), is a 243 amino acid secreted protein. Expressed in the testis and epididymis, CRISP-2 is thought to be involved in calcium fluxes during sperm capacitation by regulating the activity of certain ion channels. CRISP-3 is expressed in pancreas and prostate tissues and, along with CRISP-1, is expressed in saliva. The gene that encodes CRISP-3 is an early response gene that may participate in the pathophysiology of the auto-immune lesions of Sjogren’s syndrome.

     

     

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