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500ug
| 产品编号 | bs-14059P |
| 英文名称 | CRISP2 Antibody Blocking Peptide |
| 中文名称 | 富含半胱氨酸分泌蛋白2封闭多肽 |
| 英文别名 | Cancer/testis antigen 36; CRIS2_HUMAN; CRISP 2; CRISP-2; CRISP2; CT36; Cysteine rich secretory protein 2; Cysteine-rich secretory protein 2; GAPDL5; Glyceraldehyde 3 phosphate dehydrogenase like 5; Testis specific protein 1 (probe H4 1 p3 1); Testis specific protein TPX1; Testis-specific protein TPX-1; TPX1; TSP1. |
| 纯化方法 | HPLC |
| 研究领域 | Developmental Biology > Reproduction > Fertilisation Developmental Biology > Reproduction > Germ cell markers |
| 亚细胞定位 | Secreted. |
| 组织特异性 | Testis and epididymis. |
| 相似性 | Belongs to the CRISP family. |
| 功能 | May regulate some ion channels' activity and therebye regulate calcium fluxes during sperm capacitation. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Cysteine-rich secretory proteins (CRISPs) represent a family of evolutionarily conserved proteins which may play a role in the innate immune system and are transcriptionally regulated by androgens in several tissues. CRISP-1 coats the postacrosomal region of sperm heads as they pass through the epididymis. CRISP-1 is found in all regions of the epididymis, ductus deferens, seminal plasma and sperm. CRISP-2, also known as testis-specific protein TPX1 or cancer/testis antigen 36 (CT36), is a 243 amino acid secreted protein. Expressed in the testis and epididymis, CRISP-2 is thought to be involved in calcium fluxes during sperm capacitation by regulating the activity of certain ion channels. CRISP-3 is expressed in pancreas and prostate tissues and, along with CRISP-1, is expressed in saliva. The gene that encodes CRISP-3 is an early response gene that may participate in the pathophysiology of the auto-immune lesions of Sjogren’s syndrome. |
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CRISP2 Antibody Blocking Peptide(bs-14059P)-500ug
¥880







