Recombinant human G-CSF protein, C-His(bs-10808P)-100ug/500ug/20ug

Recombinant human G-CSF protei

n, C-His(bs-10808P)-100ug/500ug/20ug
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  • ¥580 - 5680
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  • bs-10808P
  • 2025年10月16日
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      100ug/500ug/20ug

    规格:100ug产品价格:¥1880.0
    规格:500ug产品价格:¥5680.0
    规格:20ug产品价格:¥580.0
    产品编号bs-10808P
    英文名称Recombinant human G-CSF protein, C-His
    中文名称重组人粒细胞-巨噬细胞集落刺激因子3蛋白
    英文别名G-CSF; Colony stimulating factor 3 (granulocyte); CSF 3; CSF beta; CSF3; Csfg; Filgrastim; GCSA; GCSF; Granulocyte colony stimulating factor; Lenograstim; Macrophage granulocyte inducer 2; MGC45931; MGI 2; Pluripoietin; Granulocyte Colony Stimulating Factors 3; CSF3_HUMAN; Recombinant human G-CSF protein, C-His
    性状Lyophilized or Liqui
    纯化方法AC
    理论分子量19
    实际分子量19 kDa
    浓度>0.5 mg/ml
    储存液10mM TBS (pH7.4).
    研究领域

    Cancer > Invasion/microenvironment > Angiogenesis > Angiogenic growth factors

    Immunology > Innate Immunity > Cytokines > CSFs

    亚细胞定位Secreted.
    翻译后修饰O-glycan consists of Gal-GalNAc disaccharide which can be modified with up to two sialic acid residues (done in recombinantly expressed G-CSF from CHO cells).
    相似性Belongs to the IL-6 superfamily.
    功能Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. This CSF induces granulocytes.
    保存条件Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Granulocyte-colony stimulating factor (G-CSF) is a growth factor and an essential cytokine belonging to the CSF family of hormone-like glycoproteins that regulate haematopoietic cell proliferation and differentiation. G-CSF was isolated initially as a factor supporting the growth of colonies of granulocytes in soft agar cultures. Cells of the monocyte/macrophage lineage are among the most prominent sources of G-CSF, but this factor can also be produced by normal cells of mesodermal origin, including vascular endothelial cells, fibroblasts, and mesothelial cells. Production of G-CSF can be induced in vitro in these cells by a wide variety of stimulatory agents, including LPS, TNF, IL-1, IL-3, I L-4, and IFN-Gamma. G-CSF is likely to play a role in the basal regulation of neutrophil production, and also functions as a primary regulatory factor controlling the neutrophil response to inflammatory stimuli. Furthermore, G-CSF exhibits other biological activities besides the proliferative effects, since G-CSF appears to modulate the distribution of neutrophils and progenitor cells within the body.

     

     

    Recombinant human G-CSF protei
    The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.

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