- ￥880
- Bioss
- bs-0057P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-0057P |
| 英文名称 | Amylin Antibody Blocking Peptide |
| 中文名称 | 糖尿病相关肽/胰岛淀粉样肽封闭多肽 |
| 英文别名 | Islet amyloid polypeptide; IAPP; DAP; Diabetes associated peptide; IAP; Insulinoma amyloid peptide. |
| 性状 | Lyophilized |
| 纯化方法 | HPLC |
| 研究领域 | Cardiovascular > Atherosclerosis > Diabetes associated Metabolism > Pathways and Processes > Metabolic signaling pathways > Energy transfer pathways > Energy Metabolism Metabolism > Types of disease > Diabetes Metabolism > Types of disease > Heart disease Signal Transduction > Metabolism > Energy Metabolism |
| 亚基 | Interacts with IDE and INS. Can form homodimers. Interaction with INS inhibits homodimerization and fibril formation. |
| 亚细胞定位 | Secreted. |
| 翻译后修饰 | Amyloid fibrils are degraded by IDE. |
| 相似性 | Belongs to the calcitonin family. |
| 功能 | Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | Amylin is commonly found in pancreatic islets of patients suffering diabetes mellitus type II, or harboring an insulinoma. While the assosciation of amylin with the development of type II diabetes has been known for some time, a direct causative role for amylin has been harder to establish. Recent results suggest that amylin, like the related beta amyloid (Abeta) assosciated with Alzheimer's disease, can induce apoptotic cell death in particular cultured cells, an effect that may be relevant to the development of type II diabetes. |
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Amylin Antibody Blocking Peptide(bs-0057P)-500ug
￥880
