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| 产品编号 | bs-2453P |
| 英文名称 | CCL17 Antibody Blocking Peptide |
| 中文名称 | 胸腺活化调节趋化因子封闭多肽 |
| 英文别名 | TARC; CCL17; SCYA17; ABCD-2; C-C motif chemokine 17; A152E53; CC Chemokine TARC; CCL17; Chemokine CC Motif Ligand 17; MGC138271; MGC138273; Small Inducible Cytokine A17; Small Inducible Cytokine A17 Precursor; Small Inducible Cytokine Subfamily A (Cys Cys); Small Inducible Cytokine Subfamily A (Cys Cys) Member 17; T Cell Directed CC Chemokine; Thymus and activation regulated chemokine; CCL17_HUMAN. |
| 纯化方法 | HPLC |
| 研究领域 | Immunology > Innate Immunity > Chemokines > Beta Chemokines (CC) |
| 亚细胞定位 | Secreted. |
| 组织特异性 | Expressed at high levels in thymus and at low levels in the lung, colon and small intestine. |
| 翻译后修饰 | One major form (form long), and two minor forms (short chain and medium chain) are produced by differential signal peptide cleavage. The medium chain is about 30-fold less active than the long chain. |
| 相似性 | Belongs to the intercrine beta (chemokine CC) family. |
| 功能 | Chemotactic factor for T-lymphocytes but not monocytes or granulocytes. May play a role in T-cell development in thymus and in trafficking and activation of mature T-cells. Binds to CCR4. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. TARC displays chemotactic activity for T lymphocytes, but not monocytes or granulocytes. TARC binds to chemokine receptors CCR4 and CCR8. This chemokine plays important roles in T cell development in thymus as well as in trafficking and activation of mature T cells. |
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文献和实验or from the literature are missing. In this article, processing parameters for DNA, peptide, antibody, and carbohydrate microarrays are outlined. The applicability of the model experiments is demonstrated and described in detail on the example of short oligonucleotides.
Synthesis and Probing of Membrane-bound Peptide Arrays
the stringency of the blocking conditions and make sure that the primary binding partner and detection reagent (e.g., antibody) are of high purity and are used in the highest possible dilution. Stage
Mapping Protein‐Protein Interactions with Phage‐Displayed Combinatorial Peptide Libraries
. Fack, F., Deroo, S., Kreis, S., and Muller, C.P. 2000. Heteroduplex mobility assay (HMA) pre‐screening: An improved strategy for the rapid identification of inserts selected from phage‐displayed peptide
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