TNFRSF17 Antibody Blocking Peptide(bs-24539P)-500ug

TNFRSF17 Antibody Blocking Pep

tide(bs-24539P)-500ug
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  • bs-24539P
  • 2025年10月16日
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      500ug

    产品编号bs-24539P
    英文名称TNFRSF17 Antibody Blocking Peptide
    中文名称B淋巴细胞成熟因子封闭多肽
    英文别名B cell maturation antigen; B Cell Maturation Factor; B cell maturation protein; BCM; BCMA; CD269; CD269 antigen; TNFRSF17; Tumor Necrosis Factor Receptor Member 17; Tumor necrosis factor receptor superfamily member 17; TNR17_HUMAN.
    纯化方法HPLC
    研究领域

    Cancer > Growth factors > TNF

    Immunology > Immune System Diseases > Antiviral Signaling

    Signal Transduction > Growth Factors/Hormones > TNF

    亚基Associates with TRAF1, TRAF2, TRAF3, TRAF5 and TRAF6.
    亚细胞定位Cell membrane; Single-pass type III membrane protein. Endomembrane system; Single-pass type III membrane protein.
    组织特异性Expressed in mature B-cells, but not in T-cells or monocytes.
    相似性Contains 1 TNFR-Cys repeat.
    功能Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation. [provided by RefSeq].

     

     

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