- ￥880
- Bioss
- bs-2452P
- 2025年10月16日
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-2452P |
| 英文名称 | CCL3 Antibody Blocking Peptide |
| 中文名称 | 巨噬细胞炎性蛋白1α封闭多肽 |
| 英文别名 | Tonsillar lymphocyte LD78 alpha protein; CCL 3; CCL3; Chemokine C C motif ligand 3; Chemokine CC Motif Ligand 3; G0/G1 switch regulatory protein 19 1; G0S19 1; G0S19 1 protein; Heparin binding chemotaxis protein antibody L2G25B; LD78ALPHA; Macrophage inflammatory protein 1 alpha; MIP 1 alpha; MIP-1 Alpha; MIP 1A; MIP1A; PAT 464.1; SCYA 3; SCYA3; SIS alpha; SIS beta; Small inducible cytokine A3; Tonsillar lymphocyte LD78 alpha protein; CCL3_HUMAN; CCL3_MOUSE; |
| 纯化方法 | HPLC |
| 研究领域 | Immunology > Immune System Diseases > Antiviral Signaling > HIV-related Immunology > Innate Immunity > Chemokines > Beta Chemokines (CC) Immunology > Innate Immunity > Macrophage / Inflamm. Kits/ Lysates/ Other > Kits > ELISA Kits > ELISA Kits > Blood cell antigens ELISA kits |
| 亚基 | Self-associates. Also heterodimer of MIP-1-alpha(4-69) and MIP-1-beta(3-69). |
| 亚细胞定位 | Secreted. |
| 组织特异性 | Expressed in lung, spleen, and pancreas. |
| 翻译后修饰 | N-terminal processed form LD78-alpha(4-69) is produced by proteolytic cleavage after secretion from HTLV1-transformed T-cells. |
| 相似性 | Belongs to the intercrine beta (chemokine CC) family. |
| 功能 | Monokine with inflammatory and chemokinetic properties. Binds to CCR1, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-alpha induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Macrophage Inflammatory Protein 1 alpha (MIP1 alpha) and MIP1 beta, two closely related but distinct proteins, were originally co-purified from medium conditioned by a LPS-stimulated murine macrophage cell line. Mature mouse MIP1 alpha shares approximately 77% and 70% amino acid identity with human MIP1 alpha and mouse MIP1 beta, respectively. MIP1 proteins are expressed primarily in T cells, B cells, and monocytes after antigen or mitogen stimulation. Has adhesive effects on lymphocytes. MIP1 alpha can inhibit the proliferation of hematopoietic stem cells in vitro as well as in vivo. A signal transducing receptor, designated the C-C chemokine receptor-1 (C-C CKR-1) with seven transmembrane domains that bind MIP1 alpha, MIP1 beta, MCP1 and RANTES with varying affinities, has been isolated. |
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
技术资料暂无技术资料 索取技术资料
CCL3 Antibody Blocking Peptide(bs-2452P)-500ug
￥880
