VAX1 Antibody Blocking Peptide(bs-11496P)-500ug

VAX1 Antibody Blocking Peptide

(bs-11496P)-500ug
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  • ¥880
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  • bs-11496P
  • 2025年10月16日
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      500ug

    产品编号bs-11496P
    英文名称VAX1 Antibody Blocking Peptide
    中文名称视神经视网膜相关蛋白VAX1封闭多肽
    英文别名VAX1; VAX1_HUMAN; ventral anterior homeobox 1.
    纯化方法HPLC
    亚细胞定位Nucleus.
    相似性Belongs to the EMX homeobox family.
    Contains 1 homeobox DNA-binding domain.
    功能Required for axon guidance and major tract formation in the developing forebrain. May contribute to the differentiation of the neuroretina, pigmented epithelium and optic stalk.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料The homeobox DNA-binding domain is a 60 amino acid motif that is conserved among many species and functions to bind DNA via a helix-turn-helix structure, thereby playing a role in transcriptional regulation and the control of gene expression. VAX1 (ventral anterior homeobox 1) is a 334 amino acid protein that localizes to the nucleus and contains one homeobox DNA-binding domain. Expressed as multiple alternatively spliced isoforms, VAX1 is required for major tract formation and axon guidance in the developing brain and may play a role in the differentiation of various structures, including the optic stalk, the neuroretina and the pigmented epithelium. The gene encoding VAX1 maps to human chromosome 10, which houses over 1,200 genes and comprises nearly 4.5% of the human genome.

     

     

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