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500ug
| 产品编号 | bs-11496P |
| 英文名称 | VAX1 Antibody Blocking Peptide |
| 中文名称 | 视神经视网膜相关蛋白VAX1封闭多肽 |
| 英文别名 | VAX1; VAX1_HUMAN; ventral anterior homeobox 1. |
| 纯化方法 | HPLC |
| 亚细胞定位 | Nucleus. |
| 相似性 | Belongs to the EMX homeobox family. Contains 1 homeobox DNA-binding domain. |
| 功能 | Required for axon guidance and major tract formation in the developing forebrain. May contribute to the differentiation of the neuroretina, pigmented epithelium and optic stalk. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The homeobox DNA-binding domain is a 60 amino acid motif that is conserved among many species and functions to bind DNA via a helix-turn-helix structure, thereby playing a role in transcriptional regulation and the control of gene expression. VAX1 (ventral anterior homeobox 1) is a 334 amino acid protein that localizes to the nucleus and contains one homeobox DNA-binding domain. Expressed as multiple alternatively spliced isoforms, VAX1 is required for major tract formation and axon guidance in the developing brain and may play a role in the differentiation of various structures, including the optic stalk, the neuroretina and the pigmented epithelium. The gene encoding VAX1 maps to human chromosome 10, which houses over 1,200 genes and comprises nearly 4.5% of the human genome. |
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VAX1 Antibody Blocking Peptide(bs-11496P)-500ug
¥880







