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- Bioss
- bs-2431P
- 2025年10月16日
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- 规格：
500ug
| 产品编号 | bs-2431P |
| 英文名称 | TNFSF13B Antibody Blocking Peptide |
| 中文名称 | TNF家族B细胞激活因子封闭多肽 |
| 英文别名 | ApoL related ligand TALL 1; B cell Activating Factor; B lymphocyte stimulator ; BLYS; CD 257; CD257; CD257 antigen; delta BAFF; Dendritic cell derived TNF like molecule; DTL; DTL precursor; TALL 1; TALL1; THANK; TNF and APOL related leukocyte expressed ligand 1; TNF homolog that activates apoptosis; TNF homolog that activates apoptosis NKFB and JNK; TNFSF13B; TNFSF20; Tumor necrosis factor ligand superfamily member 13B; Tumor necrosis factor ligand superfamily member 20; Tumor necrosis factor like protein ZTNF4; Tumor necrosis factor superfamily member 13B; ZTNF4; TN13B_MOUSE . |
| 性状 | Lyophilized |
| 纯化方法 | HPLC |
| 研究领域 | Cancer > Growth factors > TNF Cell Biology > Apoptosis > Extracellular Signals > Death Ligands Immunology > Adaptive Immunity > B Cells > Non-CD Immunology > Innate Immunity > Cytokines > Necrosis Factors |
| 亚基 | Belongs to the tumor necrosis factor family. |
| 亚细胞定位 | Secreted and Cell membrane. |
| 组织特异性 | Abundantly expressed in peripheral blood Leukocytes and is specifically expressed in monocytes and macrophages. Also found in the spleen, lymph node, bone marrow, T-cells and dendritic cells. A lower expression seen in placenta, heart, lung, fetal liver, thymus, and pancreas. |
| 翻译后修饰 | The soluble form derives from the membrane form by proteolytic processing. Isoform 2 is not efficiently shed from the membrane unlike isoform 1. |
| 相似性 | Belongs to the tumor necrosis factor family. |
| 功能 | Cytokine that binds to TNFRSF13B/TACI and TNFRSF17/BCMA. TNFSF13/APRIL binds to the same 2 receptors. Together, they form a 2 ligands -2 receptors pathway involved in the stimulation of B-and T-cell function and the regulation of humoral immunity. A third B-cell specific BAFF-receptor (BAFFR/BR3) promotes the survival of mature B-cells and the B-cell response. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptors TNFRSF13B/TACI, TNFRSF17/BCMA, and TNFRSF13C/BAFFR. This cytokine is expressed in B cell lineage cells, and acts as a potent B cell activator. It has been also shown to play an important role in the proliferation and differentiation of B cells. [provided by RefSeq]. |
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TNFSF13B Antibody Blocking Peptide(bs-2431P)-500ug
￥880
