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500ug
| 产品编号 | bs-12777P |
| 英文名称 | VPS45A Antibody Blocking Peptide |
| 中文名称 | 液泡蛋白分选蛋白45A封闭多肽 |
| 英文别名 | h-VPS45; H1; H1VPS45; HGNC:14579; hlVps45; Leucocyte vacuolar protein sorting 45; OTTHUMP00000014482; Vacuolar protein sorting 45 homolog (S. cerevisiae); Vacuolar protein sorting 45A (yeast homolog); Vacuolar protein sorting 45A; Vacuolar protein sorting 45B (yeast); Vacuolar protein sorting-associated protein 45; VPS45; VPS45_HUMAN; VPS45A; VPS45B; VPS54A; VSP45; VSP45A. |
| 纯化方法 | HPLC |
| 研究领域 | Signal Transduction > Protein Trafficking > Organelle Proteins Signal Transduction > Protein Trafficking > Vesicle Transport > Regulation |
| 亚细胞定位 | Golgi apparatus membrane. Endosome membrane. Associated with Golgi/endosomal vesicles and the trans-Golgi network. |
| 组织特异性 | Ubiquitous. Expression was highest in testis, heart and brain, intermediate in kidney, spleen, prostate, ovary, small intestine and thymus and low in lung, skeletal muscle, placenta, colon, pancreas, peripheral blood leukocytes and liver. |
| 相似性 | Belongs to the STXBP/unc-18/SEC1 family. |
| 功能 | May play a role in vesicle-mediated protein trafficking from the Golgi stack through the trans-Golgi network. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene is a member of the Sec1 domain family, and shows a high degree of sequence similarity to mouse, rat and yeast Vps45. The exact function of this gene is not known, but its high expression in peripheral blood mononuclear cells suggests a role in trafficking proteins, including inflammatory mediators. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2013] |
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VPS45A Antibody Blocking Peptide(bs-12777P)-500ug
¥880







