VPS45A Antibody Blocking Peptide(bs-12777P)-500ug

VPS45A Antibody Blocking Pepti

de(bs-12777P)-500ug
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  • bs-12777P
  • 2025年10月16日
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      500ug

    产品编号bs-12777P
    英文名称VPS45A Antibody Blocking Peptide
    中文名称液泡蛋白分选蛋白45A封闭多肽
    英文别名h-VPS45; H1; H1VPS45; HGNC:14579; hlVps45; Leucocyte vacuolar protein sorting 45; OTTHUMP00000014482; Vacuolar protein sorting 45 homolog (S. cerevisiae); Vacuolar protein sorting 45A (yeast homolog); Vacuolar protein sorting 45A; Vacuolar protein sorting 45B (yeast); Vacuolar protein sorting-associated protein 45; VPS45; VPS45_HUMAN; VPS45A; VPS45B; VPS54A; VSP45; VSP45A.
    纯化方法HPLC
    研究领域

    Signal Transduction > Protein Trafficking > Organelle Proteins

    Signal Transduction > Protein Trafficking > Vesicle Transport > Regulation

    亚细胞定位Golgi apparatus membrane. Endosome membrane. Associated with Golgi/endosomal vesicles and the trans-Golgi network.
    组织特异性Ubiquitous. Expression was highest in testis, heart and brain, intermediate in kidney, spleen, prostate, ovary, small intestine and thymus and low in lung, skeletal muscle, placenta, colon, pancreas, peripheral blood leukocytes and liver.
    相似性Belongs to the STXBP/unc-18/SEC1 family.
    功能May play a role in vesicle-mediated protein trafficking from the Golgi stack through the trans-Golgi network.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene is a member of the Sec1 domain family, and shows a high degree of sequence similarity to mouse, rat and yeast Vps45. The exact function of this gene is not known, but its high expression in peripheral blood mononuclear cells suggests a role in trafficking proteins, including inflammatory mediators. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2013]

     

     

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