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- Bioss
- bs-43130P
- 2025年10月16日
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- 规格：
100ug/500ug/20ug
| 规格： | 100ug | 产品价格： | ￥2280.0 |
|---|---|---|---|
| 规格： | 500ug | 产品价格： | ￥6880.0 |
| 规格： | 20ug | 产品价格： | ￥680.0 |
| 产品编号 | bs-43130P |
| 英文名称 | Recombinant mouse TNFSF13B protein, N-mFc-Flag (HEK293) |
| 中文名称 | 重组小鼠肿瘤坏死因子配体超家族成员13B蛋白 |
| 英文别名 | Tumor necrosis factor ligand superfamily member 13B; B lymphocyte stimulator; BLyS; B-cell-activating factor; B cell Activating Factor; B lymphocyte stimulator; ApoL related ligand TALL 1; BAFF; Delta BAFF; Dendritic cell-derived TNF-like molecule; TNF- and APOL-related ; eukocyte expressed ligand 1; TALL-1; CD257; CD 257; CD257 antigen; Tumor necrosis factor ligand superfamily member 13b, membrane form; Tumor necrosis factor ligand superfamily member 13b, soluble form; ZTNF4; TN13B_MOUSE; TN13B_HUMAN. |
| 性状 | Lyophilized or Liqui |
| 纯化方法 | AC |
| 理论分子量 | 48 kDa |
| 浓度 | >1mg/ml |
| 储存液 | PBS(pH=7.4). |
| 研究领域 | Cancer > Growth factors > TNF Cell Biology > Apoptosis > Extracellular Signals > Death Ligands Immunology > Adaptive Immunity > B Cells > Non-CD Immunology > Innate Immunity > Cytokines > Necrosis Factors |
| 亚基 | Belongs to the tumor necrosis factor family. |
| 亚细胞定位 | Secreted and Cell membrane. |
| 组织特异性 | Abundantly expressed in peripheral blood Leukocytes and is specifically expressed in monocytes and macrophages. Also found in the spleen, lymph node, bone marrow, T-cells and dendritic cells. A lower expression seen in placenta, heart, lung, fetal liver, thymus, and pancreas. |
| 翻译后修饰 | The soluble form derives from the membrane form by proteolytic processing. Isoform 2 is not efficiently shed from the membrane unlike isoform 1. |
| 相似性 | Belongs to the tumor necrosis factor family. |
| 功能 | Cytokine that binds to TNFRSF13B/TACI and TNFRSF17/BCMA. TNFSF13/APRIL binds to the same 2 receptors. Together, they form a 2 ligands -2 receptors pathway involved in the stimulation of B-and T-cell function and the regulation of humoral immunity. A third B-cell specific BAFF-receptor (BAFFR/BR3) promotes the survival of mature B-cells and the B-cell response. |
| 保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptors TNFRSF13B/TACI, TNFRSF17/BCMA, and TNFRSF13C/BAFFR. This cytokine is expressed in B cell lineage cells, and acts as a potent B cell activator. It has been also shown to play an important role in the proliferation and differentiation of B cells. [provided by RefSeq]. |
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
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Recombinant mouse TNFSF13B protein, N-mFc-Flag (HEK293)(bs-43130P)-100ug/500ug/20ug
￥680 - 6880
