- ￥880
- Bioss
- bs-0449P
- 2025年10月16日
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500ug
| 产品编号 | bs-0449P |
| 英文名称 | TSLP Antibody Blocking Peptide |
| 中文名称 | 胸腺基质淋巴细胞生成素-1封闭多肽 |
| 英文别名 | Thymic stromal lymphopoietin isoform 1; Thymic stromal lymphopoietin; Thymic stromal lymphopoietin protein TSLP; TSLP protein; TSLP_HUMAN. |
| 性状 | Lyophilized |
| 纯化方法 | HPLC |
| 研究领域 | Immunology > Innate Immunity > Cytokines |
| 亚基 | Interacts with a receptor composed of CRLF2 and IL7R. |
| 亚细胞定位 | Secreted. |
| 组织特异性 | Expressed in a number of tissues including heart, liver and prostate. |
| 功能 | Cytokine that induces the release of T-cell-attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c(+) dendritic cells. Can induce allergic inflammation by directly activating mast cells. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | Thymic stromal lymphopoietin (TSLP) is a novel cytokine that was found to promote the development of murine B cells in vitro. This protein, which is expressed in a number of tissues including heart, liver and prostate, prevented apoptosis and stimulated growth of the human acute myeloid leukemia (AML)-derived cell line MUTZ-3. Anti-interleukin (IL)-7 receptor antibodies (Abs) neutralized this effect indicating that TSLP binds to at least part of the IL-7 receptor complex. TSLP induced phosphorylation of signal transducer and activator of transcription (STAT)-5. |
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TSLP Antibody Blocking Peptide(bs-0449P)-500ug
￥880
