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- bs-12753P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-12753P |
| 英文名称 | POGZ Antibody Blocking Peptide |
| 中文名称 | 锌指蛋白635封闭多肽 |
| 英文别名 | KIAA0461; MGC71543; Pogo transposable element with ZNF domain; POGZ; POGZ_HUMAN; putative protein product of Nbla00003; SUHW5; suppressor of hairy wing homolog; Suppressor of hairy wing homolog 5; Zinc finger protein 280E; Zinc finger protein 635; ZNF280E; ZNF635; ZNF635M. |
| 纯化方法 | HPLC |
| 研究领域 | Epigenetics and Nuclear Signaling > Transcription > Domain Families > Zinc Finger |
| 亚细胞定位 | Nucleus. Chromosome. Cytoplasm. According to some authors, it is not localized to mitotic chromatin (PubMed:19244240). Recruited to trimethylated 'Lys-9' of histone H3. |
| 相似性 | Contains 9 C2H2-type zinc fingers. Contains 1 DDE domain. Contains 1 HTH CENPB-type DNA-binding domain. |
| 功能 | Plays a role in mitotic cell cycle progression and is involved in kinetochore assembly and mitotic sister chromatid cohesion. Probably through its association with CBX5 plays a role in mitotic chromosome segregation by regulating aurora kinase B/AURKB activation and AURKB and CBX5 dissociation from chromosome arms. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The protein encoded by this gene appears to be a zinc finger protein containing a transposase domain at the C-terminus. This protein was found to interact with the transcription factor SP1 in a yeast two-hybrid system. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Aug 2010] |
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POGZ Antibody Blocking Peptide(bs-12753P)-500ug
￥880
