KMT4 Antibody Blocking Peptide(bs-16797P)-500ug

KMT4 Antibody Blocking Peptide

(bs-16797P)-500ug
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  • bs-16797P
  • 2025年10月16日
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      500ug

    产品编号bs-16797P
    英文名称KMT4 Antibody Blocking Peptide
    中文名称组蛋白H3 K79甲基转移酶封闭多肽
    英文别名Disrupter of telomere silencing protein 1; DOT 1; DOT1; DOT1 like; DOT1 like histone H3 methyltransferase (S. cerevisiae); DOT1 like histone H3 methyltransferase; DOT1 like protein; DOT1, S. cerevisiae, homolog of; DOT1L; EC 2.1.1.43; H3 K79 HMTase; Histone H3 K79 methyltransferase; Histone H3 methyltransferase; Histone H3 methyltransferase DOT1-like; Histone lysine N methyltransferase H3 lysine 79 specific; Histone methyltransferase DOT1L; KIAA1814; DOT1L_HUMAN; KMT4; Lysine N methyltransferase 4.
    纯化方法HPLC
    研究领域

    Epigenetics and Nuclear Signaling > Chromatin Modifying Enzymes > Methylation

    Epigenetics and Nuclear Signaling > Chromatin Modifying Enzymes > Methylation > Lysine methylation

    Epigenetics and Nuclear Signaling > DNA / RNA > DNA Damage & Repair > Homologous Recomb.

    Epigenetics and Nuclear Signaling > DNA / RNA > DNA Damage & Repair > Nucl. Excision Repair

    亚基Interacts with MLLT10.
    亚细胞定位Nuclear
    相似性Belongs to the class I-like SAM-binding methyltransferase superfamily. DOT1 family.
    Contains 1 DOT1 domain.
    功能The KMT4 / Dot1 (disruptor of telomeric silencing) family are a class of histone methyltransferases that play an indirect role in chromatin silencing by targeting a conserved lysine residue in the nucleosome core. Biochemical studies suggest that recombinant Dot1 proteins are active on recombinant nucleosomes, free of any modifications.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料The protein encoded by this gene is a histone methyltransferase that methylates lysine-79 of histone H3. It is inactive against free core histones, but shows significant histone methyltransferase activity against nucleosomes. [provided by RefSeq, Aug 2011]

     

     

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