FSCN1 Antibody Blocking Peptide(bs-0796P)-500ug

FSCN1 Antibody Blocking Peptid

e(bs-0796P)-500ug
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  • bs-0796P
  • 2025年10月16日
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      500ug

    产品编号bs-0796P
    英文名称FSCN1 Antibody Blocking Peptide
    中文名称纤维束1封闭多肽
    英文别名55 kDa actin bundling protein; 55 kDa actin-bundling protein; Actin bundling protein; FAN 1; Fscin1; FAN1; Fascin 1; Fascin; Fascin homolog 1 actin bundling protein (Strongylocentrotus purpuratus); Fascin homolog 1; Fascin1; FLJ38511; FSCN 1; FSCN1; FSCN1_HUMAN; HSN; p55; Singed (Drosophila) like (sea urchin fascin homolog like); Singed drosophila homolog like; Singed like (fascin homolog sea urchin) (Drosophila); Singed like (fascin homolog sea urchin); Singed like protein; Singed-like protein; SNL; Strongylocentrotus purpuratus.
    性状Lyophilized
    纯化方法HPLC
    研究领域

    Signal Transduction > Cytoskeleton / ECM > Cytoskeleton > Microfilaments > Actin etc > Actin Binding Proteins

    亚基Associates with beta-catenin. Interacts with PLXNB3.
    亚细胞定位Cytoplasm > cytoskeleton. Cell projection > filopodium. Cell projection > invadopodium.
    组织特异性Ubiquitous.
    翻译后修饰Phosphorylation on Ser-39 inhibits the actin-binding ability of fascin.
    相似性Belongs to the fascin family.
    功能Organizes filamentous actin into bundles with a minimum of 4.1:1 actin/fascin ratio. Plays a role in the organization of actin filament bundles and the formation of microspikes, membrane ruffles, and stress fibers. Important for the formation of a diverse set of cell protrusions, such as filopodia, and for cell motility and migration.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    背景资料Human fascin is a highly conserved actin-bundling protein. Fascin, encoded by the human homolog for sn (hsn) gene, has been localized to microspikes and stress fibers of cultured cells where it is thought to be involved in the formation of microfilament bundles. It is expressed predominantly in dendritic cells. Lymphoid cells, myeloid cells and plasma cells are negative. However, Reed Sternberg cells in Hodgkin’s lymphoma are positive for fascin staining. Epstein-Barr virus may induce expression of fascin in B cells.

     

     

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