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- Bioss
- bs-16792P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-16792P |
| 英文名称 | KMT2C Antibody Blocking Peptide |
| 中文名称 | 组蛋白赖氨酸N-甲基转移酶2C封闭多肽 |
| 英文别名 | Histone-lysine N-methyltransferase MLL3; Homologous to ALR protein; KMT2C; Lysine N-methyltransferase 2C; MLL3; KMT2C_HUMAN; Myeloid/lymphoid or mixed-lineage leukemia protein 3; Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog. |
| 纯化方法 | HPLC |
| 亚细胞定位 | Nucleus. |
| 组织特异性 | Highly expressed in testis and ovary, followed by brain and liver. Also expressed in placenta, peripherical blood, fetal thymus, heart, lung and kidney. Within brain, expression was highest in hippocampus, caudate nucleus, and substantia nigra. Not detected in skeletal muscle and fetal liver. |
| 相似性 | Belongs to the histone-lysine methyltransferase family. TRX/MLL subfamily. Contains 1 A.T hook DNA-binding domain. Contains 1 DHHC-type zinc finger. Contains 6 PHD-type zinc fingers. Contains 1 post-SET domain. Contains 1 RING-type zinc finger. Contains 1 SET domain. |
| 功能 | Histone methyltransferase. Methylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Central component of the MLL2/MLL3 complex, a coactivator complex of nuclear receptors, involved in transcriptional coactivation. MLL3 may be a catalytic subunit of this complex. May be involved in leukemogenesis and developmental disorder. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene is a member of the myeloid/lymphoid or mixed-lineage leukemia (MLL) family and encodes a nuclear protein with an AT hook DNA-binding domain, a DHHC-type zinc finger, six PHD-type zinc fingers, a SET domain, a post-SET domain and a RING-type zinc finger. This protein is a member of the ASC-2/NCOA6 complex (ASCOM), which possesses histone methylation activity and is involved in transcriptional coactivation. [provided by RefSeq, Jul 2008] |
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KMT2C Antibody Blocking Peptide(bs-16792P)-500ug
￥880
