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- bs-41235P
- 2025年10月16日
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- 规格：
100ug/20ug/500ug
| 规格： | 100ug | 产品价格： | ￥1880.0 |
|---|---|---|---|
| 规格： | 20ug | 产品价格： | ￥580.0 |
| 规格： | 500ug | 产品价格： | ￥5680.0 |
| 产品编号 | bs-41235P |
| 英文名称 | Recombinant human Osteocalcin protein, N-Trx & C-His |
| 中文名称 | 重组人骨钙素蛋白 |
| 英文别名 | OSTCN_HUMAN; BGLAP; Bone Gla protein; BGP; Gamma-carboxyglutamic acid-containing protein; bone gamma-carboxyglutamate protein; OC; OCN; |
| 性状 | Lyophilized or Liqui |
| 纯化方法 | AC |
| 理论分子量 | 22.5 |
| 实际分子量 | 25kDa |
| 浓度 | ＞0.5 mg/ml |
| 研究领域 | Signal Transduction > Cytoskeleton / ECM > Extracellular Matrix > Structures > Bone Stem Cells > Mesenchymal Stem Cells > Osteogenesis |
| 亚细胞定位 | Secreted. |
| 翻译后修饰 | Gamma-carboxyglutamate residues are formed by vitamin K dependent carboxylation. These residues are essential for the binding of calcium. |
| 相似性 | Belongs to the osteocalcin/matrix Gla protein family. Contains 1 Gla (gamma-carboxy-glutamate) domain. |
| 功能 | Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium. |
| 保存条件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Osteocalcin belongs to the osteocalcin/matrix Gla protein family and constitutes 1 to 2% of the total bone protein. It is a 49 amino acid single chain vitamin K dependent protein, made by osteoblasts, and is a major component of the noncollagenous bone matrix. Post translational modification by a vitamin K dependent carboxylase produces three gamma carboxyglutamic acid residues at positions 17, 21 and 24, giving it a high affinity for calcium. It also binds strongly to apatite. |
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
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Recombinant human Osteocalcin protein, N-Trx & C-His(bs-41235P)-100ug/20ug/500ug
￥580 - 5680
