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- Bioss
- bs-11416P
- 2025年10月16日
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500ug
| 产品编号 | bs-11416P |
| 英文名称 | Cpt1c Antibody Blocking Peptide |
| 中文名称 | 脑型肉碱棕榈酰转移酶1C封闭多肽 |
| 英文别名 | CPT1-C; Carnitine acyltransferase like protein 1; Carnitine acyltransferase like protein1; Carnitine O palmitoyltransferase I, brain isoform; Carnitine palmitoyltransferase 1, brain; Carnitine palmitoyltransferase 1C; Carnitine palmitoyltransferase I related C; Carnitine palmitoyltransferase1C; CAT L1; CATL 1; CATL1; CPT 1 like pseudogene; Cpt 1c; CPT 1P; CPT I C; Cpt1 c; CPT1 like pseudogene; CPT1P ; CPTIC.CPT1C_HUMAN |
| 纯化方法 | HPLC |
| 研究领域 | Cardiovascular > Lipids / Lipoproteins > Fatty Acids > Metabolism Metabolism > Pathways and Processes > Metabolic signaling pathways > Energy transfer pathways > Energy Metabolism Metabolism > Pathways and Processes > Metabolic signaling pathways > Lipid and lipoprotein metabolism > Fatty acids Metabolism > Pathways and Processes > Mitochondrial Metabolism > Mitochondrial markers Metabolism > Pathways and Processes > Redox metabolism > Fatty acid oxidation Metabolism > Types of disease > Obesity Neuroscience > Endocrine system > Hypothalamic pituitary adrenal axis Neuroscience > Neurology process > Metabolism Signal Transduction > Metabolism > Energy Metabolism Signal Transduction > Metabolism > Lipid metabolism Signal Transduction > Metabolism > Mitochondrial |
| 亚细胞定位 | Mitochondrion outer membrane; Multi-pass membrane protein |
| 组织特异性 | Expressed predominantly in brain and testis. |
| 相似性 | Belongs to the carnitine/choline acetyltransferase family. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The Cpt1 family of proteins are outer mitochondrial membrane proteins that regulate the entry into, and oxidation of fatty acids by, mitochondria. Malonyl-CoA, an intermediate in fatty acid synthesis, has been implicated as a regulatory component of the energy sensing system that feeds into hypothalmic neurons to impart energy homeostasis. Malonyl-CoA levels in the hypothalamus are dynamically regulated by fasting and feeding, altering subsequent feeding behaviour. Cpt1c, the brain-specific carnitine O-palmitoyltransferase 1, is thought to relay information about malonyl-CoA levels in hypothalamic neurons that express orexigenic and anorexigenic neuropeptides that regulate food intake and peripheral energy expenditure. Unlike other Cpt1 proteins, Cpt1c binds Malonyl-CoA but does not catalyse the transfer of the malonyl group from CoA to carnitine. |
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