- ￥880
- Bioss
- bs-11405P
- 2025年10月16日
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500ug
| 产品编号 | bs-11405P |
| 英文名称 | GPCR GPCR135 Antibody Blocking Peptide |
| 中文名称 | G蛋白偶联受体135/松弛素受体3封闭多肽 |
| 英文别名 | Relaxin Receptor 3; G protein coupled receptor GPCR135; G protein coupled receptor SALPR; G-protein coupled receptor SALPR; GPCR SALPR; GPCR 135; GPCR135; Gprotein coupled receptor SALPR; Relaxin 3 receptor 1; Relaxin 3 receptor1; Relaxin 3/INSL7 receptor 1; Relaxin 3/INSL7 receptor1; Relaxin family peptide receptor 3; Relaxin family peptide receptor3; Relaxin/insulin like family peptide receptor 3; Relaxin3 receptor 1; Relaxin3 receptor1; RL3 R1; RL3R 1; RL3R1; RLN3 receptor 1; RLN3 receptor1; RLN3R1; RXFPR3; SALP R; SALPR; somatostatin and angiotensin like peptide receptor; RL3R1_HUMAN. |
| 纯化方法 | HPLC |
| 研究领域 | Developmental Biology > Reproduction > Hormones Neuroscience > Endocrine system > Gonadotrophic axis Neuroscience > Neurology process > Metabolism Neuroscience > Neurotransmitter > Neuropeptides > Hormones Signal Transduction > Growth Factors/Hormones > Insulin / Insulin-like Signal Transduction > Signaling Pathway > G Protein Signaling > GPCR |
| 亚细胞定位 | Cell membrane; Multi-pass membrane protein. |
| 组织特异性 | Expressed predominantly in brain regions. Highest expression in substantia nigra and pituitary, followed by hippocampus, spinal cord, amygdala, caudate nucleus and corpus callosum, quite low level in cerebellum. In peripheral tissues, relatively high levels in adrenal glands, low levels in pancreas, salivary gland, placenta, mammary gland and testis. |
| 相似性 | Belongs to the G-protein coupled receptor 1 family. |
| 功能 | GPCR SALPR, also known as Relaxin 3 Receptor 1 (RXFP3), is a G-protein coupled receptor that is one of the physiological targets for relaxin 3, an insulin-like hormone. Activation of GPCR SALPR results in phosphorylation of ERK1/2. GPCR SALPR has been implicated in anxiety and obesity. A role for relaxin 3 and GPCR SALPR in reproductive function through the hypothalamic-pituitary-gonadal (HPG) axis has also been described. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Relaxin Receptor 3 is a G protein-coupled receptor that binds Relaxin 3 and influences differentiation and maintenance of the nervous system. Relaxin Receptor 3 shares sequence similarity with somatostatin receptors and angiotensin receptors. It mediates central processing of sensory signals in the rat and is thought to be a modulator of stress responses. Relaxin Receptor 3 is present in the brain, with highest expression in substantia nigra and pituitary, followed by hippocampus, spinal cord, amygdala, caudate nucleus and corpus callosum, and low level expression in cerebellum. In peripheral tissues there are high levels in adrenal glands and low levels in pancreas, salivery gland, placenta, mammary gland and testis. |
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GPCR GPCR135 Antibody Blocking Peptide(bs-11405P)-500ug
￥880
