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- Bioss
- bs-24340P
- 2025年10月16日
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- 规格：
500ug
| 产品编号 | bs-24340P |
| 英文名称 | RASAL1 Antibody Blocking Peptide |
| 中文名称 | RAS蛋白样激活剂1封闭多肽 |
| 英文别名 | GAP1 like protein; MRASAL; RAS GTPase activating protein like; RAS protein activator like 1 (GAP1 like); RAS protein activator like 1; RASAL; Rasal1; rasGAP activating like protein 1; RasGAP-activating-like protein 1; RASGAP1 LIKE; RASL1_HUMAN. |
| 纯化方法 | HPLC |
| 研究领域 | Cancer > Oncoproteins/suppressors > Tumor suppressors Signal Transduction > Signaling Pathway > G Protein Signaling > Small G Proteins > Regulators |
| 组织特异性 | Highly expressed in thyroid and adrenal medulla, lower expression in brain, spinal cord and trachea. |
| 相似性 | Contains 1 Btk-type zinc finger. Contains 2 C2 domains. Contains 1 PH domain. Contains 1 Ras-GAP domain. |
| 功能 | Probable inhibitory regulator of the Ras-cyclic AMP pathway. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Ras GTPase activating-like protein (RASAL) or RASAL1 is a member of the GAP1 family, and a Ca2+ sensor responding in-phase to repetitive Ca2+ signals by associating with the plasma membrane and deactivating Ras. It contains a conserved domain structure comprising N-terminal tandem C2 domains, a highly conserved central RasGAP domain, and a C-terminal pleckstrin-homology domain that is associated with a Bruton's tyrosine kinase motif. RASAL, like Ca2+ -promoted Ras inactivator (CAPRI, or RASAL4), is a cytosolic protein that undergoes a rapid translocation to the plasma membrane in response to receptor-mediated elevation in the concentration of intracellular free Ca2+, a translocation that activates its ability to function as a RasGAP. However, unlike RASAL4, RASAL undergoes an oscillatory translocation to the plasma membrane that occurs in synchrony with repetitive Ca2+ spikes. |
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RASAL1 Antibody Blocking Peptide(bs-24340P)-500ug
￥880
