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- Bioss
- bs-12713P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-12713P |
| 英文名称 | PLCD3 Antibody Blocking Peptide |
| 中文名称 | 磷酸肌醇磷脂酶c-delta-3封闭多肽 |
| 英文别名 | PLC-delta-3; 1-phosphatidylinositol-4 ; 5-bisphosphate phosphodiesterase delta-3 ; Phosphoinositide phospholipase C-delta-3 ; Phospholipase C-delta-3 ; PLC-delta-3 ; PLCD3 ; PLCD3_HUMAN. |
| 纯化方法 | HPLC |
| 研究领域 | Signal Transduction > Second Messenger > Lipid Messengers Signal Transduction > Signaling Pathway > Calcium Signaling > Calcium Binding Proteins Signal Transduction > Signaling Pathway > Lipid Signaling |
| 亚细胞定位 | Membrane. Cytoplasm. Cleavage furrow. Localizes at the cleavage furrow during cytokinesis. |
| 组织特异性 | Present in corneal epithelial cells (at protein level). |
| 相似性 | Contains 1 C2 domain. Contains 3 EF-hand domains. Contains 1 PH domain. Contains 1 PI-PLC X-box domain. Contains 1 PI-PLC Y-box domain. |
| 功能 | Hydrolyzes the phosphatidylinositol 4,5-bisphosphate (PIP2) to generate 2 second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). DAG mediates the activation of protein kinase C (PKC), while IP3 releases Ca(2+) from intracellular stores. Essential for trophoblast and placental development. May participate in cytokinesis by hydrolyzing PIP2 at the cleavage furrow. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes a member of the phospholipase C family, which catalyze the hydrolysis of phosphatidylinositol 4,5-bisphosphate to generate the second messengers diacylglycerol and inositol 1,4,5-trisphosphate (IP3). Diacylglycerol and IP3 mediate a variety of cellular responses to extracellular stimuli by inducing protein kinase C and increasing cytosolic Ca(2+) concentrations. This enzyme localizes to the plasma membrane and requires calcium for activation. Its activity is inhibited by spermine, sphingosine, and several phospholipids. [provided by RefSeq, Jul 2008 |
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PLCD3 Antibody Blocking Peptide(bs-12713P)-500ug
￥880
