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- Bioss
- bs-12711P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-12711P |
| 英文名称 | PKP4 Antibody Blocking Peptide |
| 中文名称 | 桥粒斑菲素蛋白4封闭多肽 |
| 英文别名 | Catenin 4 ; Catenin4 ; FLJ31261 ; FLJ42243 ; p0071 ; PKP 4 ; PKP4 ; PKP4_HUMAN ; Plakophilin-4 ; Plakophilin4. |
| 纯化方法 | HPLC |
| 研究领域 | Signal Transduction > Cytoskeleton / ECM > Extracellular Matrix > Structures > Desmosomes |
| 亚细胞定位 | Cell junction > desmosome. Colocalized with desmoplakin at desmosomal junctional plaques in cultured epithelial cells. |
| 翻译后修饰 | Phosphorylated upon DNA damage, probably by ATM or ATR. |
| 相似性 | Belongs to the beta-catenin family. Contains 9 ARM repeats. |
| 功能 | May play a role in junctional plaques. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Armadillo-like proteins are characterized by a series of armadillo repeats, first defined in the Drosophila 'armadillo' gene product, that are typically 42 to 45 amino acids in length. These proteins can be divided into subfamilies based on their number of repeats, their overall sequence similarity, and the dispersion of the repeats throughout their sequences. Members of the p120(ctn)/plakophilin subfamily of Armadillo-like proteins, including CTNND1, CTNND2, PKP1, PKP2, PKP4, and ARVCF. PKP4 may be a component of desmosomal plaque and other adhesion plaques and is thought to be involved in regulating junctional plaque organization and cadherin function. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2015] |
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PKP4 Antibody Blocking Peptide(bs-12711P)-500ug
￥880
