- ￥880
- Bioss
- bs-1792P
- 2025年10月16日
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-1792P |
| 英文名称 | CK14/17/42 Antibody Blocking Peptide |
| 中文名称 | 细胞角蛋白14封闭多肽 |
| 英文别名 | Cytokeratin 14; CK 14; ck14; Cytokeratin14; Cytokeratin-14; Dowling Meara; ebs3; Epidermolysis bullosa simplex; k14; Keratin 14; Keratin type I cytoskeletal 14; Keratin14; Koebner; Krt 14; krt14; EBS3; EBS4; NFJ; Keratin, type I cytoskeletal 14; Cytokeratin 17; CK 17; ck17; Cytokeratin17; Cytokeratin-17; Keratin, type I cytoskeletal 17; Cytokeratin 10; CK 10; ck10; Cytokeratin10; Cytokeratin-10; Keratin, type I cytoskeletal 10; Cytokeratin 42; CK 42; ck42; Cytokeratin42; Cytokeratin-42; Keratin, type I cytoskeletal 42; K1C14_HUMAN. |
| 性状 | Lyophilized |
| 纯化方法 | HPLC |
| 研究领域 | Signal Transduction > Cytoskeleton / ECM > Cytoskeleton > Intermediate Filaments > Class I > Cytokeratins |
| 亚基 | Heterotetramer of two type I and two type II keratins. keratin-14 associates with keratin-5. Interacts with TRADD and with keratin filaments. Associates with other type I keratins. |
| 亚细胞定位 | Cytoplasm. Nucleus. Note=Expressed in both as a filamentous pattern. |
| 组织特异性 | Detected in the basal layer, lowered within the more apically located layers specifically in the stratum spinosum, stratum granulosum but is not detected in stratum corneum. Strongly expressed in the outer root sheath of anagen follicles but not in the germinative matrix, inner root sheath or hair. Found in keratinocytes surrounding the club hair during telogen. |
| 翻译后修饰 | A disulfide bond is formed between rather than within filaments and promotes the formation of a keratin filament cage around the nucleus. |
| 相似性 | Belongs to the intermediate filament family. |
| 功能 | The nonhelical tail domain is involved in promoting KRT5-KRT14 filaments to self-organize into large bundles and enhances the mechanical properties involved in resilience of keratin intermediate filaments in vitro. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | This gene encodes a member of the keratin family, the most diverse group of intermediate filaments. This gene product, a type I keratin, is usually found as a heterotetramer with two keratin 5 molecules, a type II keratin. Together they form the cytoskeleton of epithelial cells. Mutations in the genes for these keratins are associated with epidermolysis bullosa simplex. At least one pseudogene has been identified at 17p12-p11. [provided by RefSeq]. |
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
技术资料暂无技术资料 索取技术资料
CK14/17/42 Antibody Blocking Peptide(bs-1792P)-500ug
￥880
