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- Bioss
- bs-16767P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-16767P |
| 英文名称 | KLHL2 Antibody Blocking Peptide |
| 中文名称 | Kelch样蛋白2封闭多肽 |
| 英文别名 | ABP KELCH; Actin binding protein Mayven; Actin-binding protein Mayven; kelch; kelch like 2; Kelch like protein 2; Kelch-like protein 2; KLHL2; KLHL2_HUMAN; MAV; MAYVEN; OTTHUMP00000219997; OTTHUMP00000219998. |
| 纯化方法 | HPLC |
| 研究领域 | Signal Transduction > Cytoskeleton / ECM > Cytoskeleton > Microfilaments > Actin etc > Actin Binding Proteins |
| 亚细胞定位 | Cytoplasm > cytoskeleton. |
| 组织特异性 | Predominantly expressed in brain. |
| 相似性 | Contains 1 BTB (POZ) domain. Contains 6 Kelch repeats. |
| 功能 | May play a role in organizing the actin cytoskeleton of the brain cells. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | KLHL2 is a 593 amino acid actin-binding protein. Highly expressed in brain, KLHL2 is thought to play a role in the organization of the actin cytoskeleton in brain cells. KLHL3 (kelch-like protein 3), is a 587 amino acid protein active in the protein ubiquitination pathway. KLHL3 is thought to be a substrate-specific adapter of an E3 ubiquitin-ligase complex that mediates the ubiquitination of target proteins, which leads to proteasomal degradation of the target protein. KLHL2 and KLHL3 proteins contain six kelch repeats and one BTB (POZ) domain. The BTB (Broad-Complex, Tramtrack and Bric a brac) domain, also known as the POZ (Poxvirus and Zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. |
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KLHL2 Antibody Blocking Peptide(bs-16767P)-500ug
￥880
