KLHDC10 Antibody Blocking Peptide(bs-16757P)-500ug

KLHDC10 Antibody Blocking Pept

ide(bs-16757P)-500ug
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  • ¥880
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  • bs-16757P
  • 2025年10月16日
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      500ug

    产品编号bs-16757P
    英文名称KLHDC10 Antibody Blocking Peptide
    中文名称KLHDC10蛋白封闭多肽
    英文别名Kelch domain containing 10; Kelch domain-containing protein 10; KIAA0265; KLD10_HUMAN; Klhdc10; OTTHUMP00000212347; PNAS 119; Scruin like at the midline homolog; Slim.
    纯化方法HPLC
    亚基Interacts with CUL2, TCEB1 and TCEB2; may be the substrate recognition component of an E3 ubiquitin ligase complex.
    亚细胞定位Nucleus
    相似性Contains 6 Kelch repeats.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料KLHDC10 is a 442 amino acid protein that contains six kelch repeats. Expressed in fetal brain, liver, lung, kidney and placenta, KLHDC10 exists as two alternatively spliced isoforms. The gene encoding KLHDC10 maps to human chromosome 7, which houses over 1,000 genes and comprises nearly 5% of the human genome. Chromosome 7 has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. The deletion of a portion of the q arm of chromosome 7 is associated with Williams-Beuren syndrome, a condition characterized by mild mental retardation, an unusual comfort and friendliness with strangers and an elfin appearance. Deletions of portions of the q arm of chromosome 7 are also seen in a number of myeloid disorders, including cases of acute myelogenous leukemia and myelodysplasia.

     

     

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