- ￥880
- Bioss
- bs-13974P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-13974P |
| 英文名称 | CARD16 Antibody Blocking Peptide |
| 中文名称 | Caspase抑制剂COP蛋白封闭多肽 |
| 英文别名 | CAR16_HUMAN; CARD only domain-containing protein 1; CARD only protein; Caspase recruitment domain family, member 16; Caspase recruitment domain-containing protein 16; Caspase-1 dominant-negative inhibitor pseudo-ICE; Caspase-1 inhibitor COP; COP; COP1; Pseudo interleukin-1 beta converting enzyme; Pseudo interleukin-1beta converting enzyme; PSEUDO-ICE. |
| 纯化方法 | HPLC |
| 组织特异性 | Widely expressed. Expressed at higher level in placenta, spleen, lymph node and bone marrow. Weakly or not expressed in thymus. |
| 相似性 | Contains 1 CARD domain. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Caspase inhibitor. Acts as a regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-interleukin-1 beta (IL1B) and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. Also induces NF-kappa-B activation during the pro-inflammatory cytokine response. Also able to inhibit CASP1-mediated neuronal cell death, TNF-alpha, hypoxia-, UV-, and staurosporine-mediated cell death but not ER stress-mediated cell death. Acts by preventing activation of caspases CASP1 and CASP4, possibly by preventing the interaction between CASP1 and RIPK2. |
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CARD16 Antibody Blocking Peptide(bs-13974P)-500ug
￥880
