- ￥880
- Bioss
- bs-1155P
- 2025年10月16日
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- 规格：
500ug
| 产品编号 | bs-1155P |
| 英文名称 | ASCL1 Antibody Blocking Peptide |
| 中文名称 | 神经母细胞特异性转移因子封闭多肽 |
| 英文别名 | Achaete scute complex homolog 1; MASH1; MASH1/Achaete-scute homolog 1; Achaete scute complex homolog like 1; Achaete scute complex homologue 1; Achaete scute complex homologue like 1; Ascl 1; Ascl1; Ash 1; Ash1; Hash 1;Hash1; Mammalian achaete scute homolog 1; Mammalian achaete scute homologue 1; Mash 1; Achaete-scute homolog 1; ASCL1_HUMAN; ASH-1; hASH1; Class A basic helix-loop-helix protein 46; bHLHa46. |
| 性状 | Lyophilized |
| 纯化方法 | HPLC |
| 研究领域 | Epigenetics and Nuclear Signaling > Transcription > Domain Families > HLH / Leucine Zipper > HLH Neuroscience > Neurology process > Neurogenesis |
| 亚基 | Efficient DNA binding requires dimerization with another bHLH protein. Forms a heterodimer with TCF3. |
| 亚细胞定位 | Nucleus (Probable). |
| 相似性 | Contains 1 basic helix-loop-helix (bHLH) domain. |
| 功能 | Transcriptional regulator. May play a role at early stages of development of specific neural lineages in most regions of the CNS, and of several lineages in the PNS. Essential for the generation of olfactory and autonomic neurons. Involved in the initiation of neuronal differentiation. Mediates transcription activation by binding to the E box (5'-CANNTG-3'). |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | This gene encodes a member of the basic helix-loop-helix (BHLH) family of transcription factors. The protein activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. This protein plays a role in the neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. Mutations in this gene may contribute to the congenital central hypoventilation syndrome (CCHS) phenotype in rare cases. [provided by RefSeq, Jul 2008] |
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ASCL1 Antibody Blocking Peptide(bs-1155P)-500ug
￥880
