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- 规格:
500ug
| 产品编号 | bs-15263P |
| 英文名称 | C7orf30 Antibody Blocking Peptide |
| 中文名称 | 7号染色体开放阅读框30封闭多肽 |
| 英文别名 | C7orf30; MASU1_HUMAN; Chromosome 7 open reading frame 30; Uncharacterized protein C7orf30. |
| 纯化方法 | HPLC |
| 亚基 | Associates with the mitochondrial ribosome large subunit (39S). Interacts with MRPL12 and MRPL14. |
| 亚细胞定位 | Mitochondrion matrix. Note=Colocalizes with MRPL12 (PubMed:22238375) and/or MRPL14 (PubMed:22829778). |
| 相似性 | Belongs to the Iojap/RsfS family. |
| 功能 | May function as a ribosomal silencing factor. Addition to isolated mitochondrial ribosomal subunits partially inhibits translation. Interacts with mitochondrial ribosomal protein L14 (MRPL14), probably blocking formation of intersubunit bridge B8, preventing association of the 28S and 39S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. May also participate in the assembly and/or regulation of the stability of the large subunit of the mitochondrial ribosome. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Chromosome 7 has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. The deletion of a portion of the q arm of chromosome 7 is associated with Williams-Beuren syndrome, a condition characterized by mild mental retardation, an unusual comfort and friendliness with strangers and an elfin appearance. Deletions of portions of the q arm of chromosome 7 are also seen in a number of myeloid disorders including cases of acute myelogenous leukemia and myelodysplasia. The C7orf30 gene product has been provisionally designated C7orf30 pending further characterization. |
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C7orf30 Antibody Blocking Peptide(bs-15263P)-500ug
¥880





