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- Bioss
- bs-15256P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-15256P |
| 英文名称 | C7 Antibody Blocking Peptide |
| 中文名称 | 补体C7封闭多肽 |
| 英文别名 | C7; CO7_HUMAN; complement component 7; Complement component C7. |
| 纯化方法 | HPLC |
| 研究领域 | Immunology > Innate Immunity > Complement > MAC |
| 亚基 | Monomer or dimer; as a C5b-7 complex it can also form multimeric rosettes. MAC assembly is initiated by protelytic cleavage of C5 into C5a and C5b. C5b binds sequentially C6, C7, C8 and multiple copies of the pore-forming subunit C9. |
| 亚细胞定位 | Secreted. |
| 翻译后修饰 | C7 has 28 disulfide bridges. O- and C-glycosylated. O-glycosylated with core 1 or possibly core 8 glycans. |
| 相似性 | Belongs to the complement C6/C7/C8/C9 family. Contains 1 EGF-like domain. Contains 1 LDL-receptor class A domain. Contains 1 MACPF domain. Contains 2 Sushi (CCP/SCR) domains. Contains 2 TSP type-1 domains. |
| 功能 | Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C7 serves as a membrane anchor. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | C7 is a component of the complement system. It participates in the formation of Membrane Attack Complex (MAC). People with C7 deficiency are prone to bacterial infection. [provided by RefSeq, Jul 2008] |
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C7 Antibody Blocking Peptide(bs-15256P)-500ug
￥880
