DLK1 Antibody Blocking Peptide(bs-2423P)-500ug

DLK1 Antibody Blocking Peptide

(bs-2423P)-500ug
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  • ¥880
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  • bs-2423P
  • 2025年10月16日
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      500ug

    产品编号bs-2423P
    英文名称DLK1 Antibody Blocking Peptide
    中文名称穿膜蛋白DLK1封闭多肽
    英文别名Adipocyte differentiation inhibitor protein; Brevideltin; Delta like 1 homolog; Delta like homolog; Delta like protein; Delta1; DLK 1; DLK; DLK-1; Dlk1; DLK1_HUMAN; FA 1; FA1; Fetal antigen 1; pG2; Preadipocyte factor 1; Pref 1; Pref; Pref1; Pref-1; Protein delta homolog 1; Secredeltin; ZOG; Delta1; PREF1.
    纯化方法HPLC
    研究领域

    Neuroscience > Endocrine system > Hypothalamic pituitary adrenal axis

    Neuroscience > Neurology process > Neurogenesis

    Signal Transduction > Signaling Pathway > Calcium Signaling > Calcium Binding Proteins

    Stem Cells > Hematopoietic Progenitors > Surface Molecules

    亚基Monomer.
    亚细胞定位Membrane; Single-pass type I membrane protein.
    组织特异性Highly expressed in fetal liver, placenta, adult adrenal gland, brain, testis and ovary and, to a lesser degree, in adult kidney, muscle, thymus and heart.
    翻译后修饰N- and O-glycosylated.
    相似性Contains 6 EGF-like domains.
    功能May have a role in neuroendocrine differentiation. Inhibits adipocyte differentiation.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料This gene encodes a transmembrane protein containing six epidermal growth factor repeats. The protein is involved in the differentiation of several cell types, including adipocytes; it is also thought to be a tumor suppressor. It is one of several imprinted genes located in a region of on chr 14q32. Certain mutations in this imprinted region can cause phenotypes similar to maternal and paternal uniparental disomy of chromosome 14 (UPD14). This gene is expressed from the paternal allele. A polymorphism within this gene has been associated with child and adolescent obesity. The mode of inheritance for this polymorphism is polar overdominance; this non-Mendelian inheritance pattern was first described in sheep with the callipyge phenotype, which is characterized by muscle hypertrophy and decreased fat mass. [provided by RefSeq, Mar 2010].

     

     

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