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- bs-12660P
- 2025年10月16日
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- 规格：
500ug
| 产品编号 | bs-12660P |
| 英文名称 | SNRPB Antibody Blocking Peptide |
| 中文名称 | 小核糖核蛋白SNRPB封闭多肽 |
| 英文别名 | B polypeptide of Sm protein; COD; RSMB_HUMAN; Sm B/B'; Sm B/Sm B'; Sm B/SmB'; Sm protein B/B''; Sm-B/B''; Small nuclear ribonucleoprotein polypeptide B; Small nuclear ribonucleoprotein polypeptide B/B'; Small nuclear ribonucleoprotein polypeptides B and B'; Small nuclear ribonucleoprotein polypeptides B and B1; Small nuclear ribonucleoprotein-associated proteins B and B''; SmB; SmB/B''; SmB/Sm B'; SmB/SmB'; snRNP B; snRNP-B; snRNPB; SNRPB; SNRPB1. |
| 纯化方法 | HPLC |
| 研究领域 | Epigenetics and Nuclear Signaling > DNA / RNA > RNA Processing > Splicing Immunology > Immune System Diseases > Autoimmune |
| 亚细胞定位 | Nucleus. |
| 翻译后修饰 | Methylated. Arg-108 and Arg-112 are dimethylated, probably to asymmetric dimethylarginine. |
| 相似性 | Belongs to the snRNP SmB/SmN family. |
| 功能 | Appears to function in the U7 snRNP complex that is involved in histone 3'-end processing. Associated with snRNP U1, U2, U4/U6 and U5. May have a functional role in the pre-mRNA splicing or in snRNP structure. Binds to the downstream cleavage product (DCP) of histone pre-mRNA in a U7 snRNP dependent manner. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The protein encoded by this gene is one of several nuclear proteins that are found in common among U1, U2, U4/U6, and U5 small ribonucleoprotein particles (snRNPs). These snRNPs are involved in pre-mRNA splicing, and the encoded protein may also play a role in pre-mRNA splicing or snRNP structure. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. Two transcript variants encoding different isoforms (B and B') have been found for this gene. [provided by RefSeq, Jul 2008] |
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SNRPB Antibody Blocking Peptide(bs-12660P)-500ug
￥880
