CRIM-1 Antibody Blocking Peptide(bs-2034P)-500ug

CRIM-1 Antibody Blocking Pepti

de(bs-2034P)-500ug
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  • ¥880
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  • bs-2034P
  • 2025年10月16日
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      500ug

    产品编号bs-2034P
    英文名称CRIM-1 Antibody Blocking Peptide
    中文名称富含半胱氨酸运动神经元蛋白1封闭多肽
    英文别名Cysteine-rich motor neuron 1 protein; CRIM-1; Cysteine-rich repeat-containing protein S52; Processed cysteine-rich motor neuron 1protein; CRIM 1; CRIM1; Cysteine rich motor neuron 1 protein; Cysteine rich repeat containing protein S52; Cysteine rich transmembrane BMP regulator 1 (chordin like); Cysteine rich transmembrane BMP regulator 1; MGC138194; Processed cysteine rich motor neuron 1 protein; S52; CRIM1_HUMAN.
    性状Lyophilized
    纯化方法HPLC
    研究领域

    Cardiovascular > Angiogenesis > Angiogenic Factors

    Neuroscience > Neurology process > Neurogenesis

    Signal Transduction > Cytoskeleton / ECM > Extracellular Matrix > Structures > Bone

    亚细胞定位Secreted and Cell membrane.
    组织特异性Expressed in pancreas, kidney, skeletal muscle, lung, placenta, brain, heart, spleen, liver and small intestine. Expressed in blood vessels (at protein level).
    翻译后修饰N-glycosylated.
    相似性Contains 4 antistasin-like domains.
    Contains 1 IGFBP N-terminal domain.
    Contains 6 VWFC domains.
    功能May play a role in CNS development by interacting with growth factors implicated in motor neuron differentiation and survival.
    May play a role in capillary formation and maintenance during angiogenesis.
    Modulates BMP activity by affecting its processing and delivery to the cell surface.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    背景资料CRIM1 interacts with BMP4 (bone morphogenic protein 4) and BMP7 and modulates BMP activity by affecting their processing and delivery to the cell surface. By interacting with growth factors implicated in motor neuron differentiation and survival, it may play a role in CNS development. It may also play a role in capillary formation and maintenance during angiogenesis.

     

     

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